An XX male with an intratubular undifferentiated germ cell neoplasia Atilano Carcavilla, M.D., Milagros Alonso, M.D., Ph.D., Begoña Ezquieta, M.D., Ph.D., Eva García-Galloway, Ph.D., Raquel Barrio, M.D., Ph.D., Manuel Nistal, M.D., Ph.D.  Fertility and Sterility  Volume 90, Issue 5, Pages 2005.e3-2005.e5 (November 2008) DOI: 10.1016/j.fertnstert.2008.07.001 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (a) Testicular dysgenesis. Anastomizing seminiferous tubules in a poorly collagenized albuginea. (b) Tubular structure in the outer zone of the albuginea resembling a fallopian tube. (Both from testicular biopsy undergone by the age of 5 months.) (c) Intratubular undifferentiated germ cell neoplasia. Large germ cells showing nuclei with irregular outlines and prominent nucleoli. (d) Intratubular undifferentiated germ cell neoplasia. Atypical germ cells showing immunostaining for C-kit. (Both from orchiectomy undergone by the age of 18 years.) (e) SRY probe (red) at the short arm of the deleted X chromosome (green). (f) Location of searched genes/locus on Y chromosome. A = absent; P = present. Fertility and Sterility 2008 90, 2005.e3-2005.e5DOI: (10.1016/j.fertnstert.2008.07.001) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions