Fertility and Sterility Efficacy of anti-tumor necrosis factor therapy in the treatment of spontaneous endometriosis in baboons  Breton F Barrier, M.D., G.Wright Bates, M.D., M.Michelle Leland, D.V.M., D.Alan Leach, M.D., Randal D Robinson, M.D., Anthony M Propst, M.D.  Fertility and Sterility  Volume 81, Pages 775-779 (March 2004) DOI: 10.1016/j.fertnstert.2003.09.034

FIGURE 1 Pre- and posttreatment lesion surface area in animals treated with either etanercept (brown and light brown bars, n = 7) or vehicle (purple and light purple bars, n = 4). Barrier. Anti-TNF therapy for endometriosis.Fertil Steril 2004. Fertility and Sterility 2004 81, 775-779DOI: (10.1016/j.fertnstert.2003.09.034)

FIGURE 2 Percent change in red lesion surface area between first and second laparoscopy in animals treated with etanercept (brown bar) and with placebo (purple bar). Barrier. Anti-TNF therapy for endometriosis.Fertil Steril 2004. Fertility and Sterility 2004 81, 775-779DOI: (10.1016/j.fertnstert.2003.09.034)

FIGURE 3 Concentration (trough)-time curves of animals treated with etanercept (n = 7). Each line represents one animal. Only one animal (9490, dark blue diamond) was unable to maintain a measurable serum concentration of etanercept. Barrier. Anti-TNF therapy for endometriosis.Fertil Steril 2004. Fertility and Sterility 2004 81, 775-779DOI: (10.1016/j.fertnstert.2003.09.034)