Cells of the innate and adaptive immune systems.

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Presentation transcript:

Cells of the innate and adaptive immune systems. Cells of the innate and adaptive immune systems. The innate immune system provides an immediate response to foreign targets, with responses typically within minutes to hours. It consists of a number of soluble factors and proteins as well as a diverse set of cells, including granulocytes, macrophages, dendritic cells and natural killer cells. The second branch of the immune system is the adaptive or acquired immune system, which provides specific, long-lasting immune responses. The adaptive and innate immune systems are linked; for example dendritic cells are important adaptive immune system cell activators. The adaptive immune system consists of antibodies, B cells, and CD4+ and CD8+ T cells, and these enable a highly specific response against a particular target. Natural killer T cells and γδ T cells are cytotoxic lymphocytes that overlap both innate and adaptive immunity. Cells from both arms of the immune system are in development as potential cellular immunotherapies. Michaela Sharpe, and Natalie Mount Dis. Model. Mech. 2015;8:337-350 © 2015. Published by The Company of Biologists Ltd