A common pathway for genetic events leading to pheochromocytoma

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A common pathway for genetic events leading to pheochromocytoma Patrick H. Maxwell Cancer Cell Volume 8, Issue 2, Pages 91-93 (August 2005) DOI: 10.1016/j.ccr.2005.07.012 Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 1 As NGF levels become limiting during development, mutations affecting NF1, RET, VHL, and SDH subunits all decrease apoptosis mediated by SM-20/EglN3/PHD3. Adapted from Lee et al. (2005) to show interactions with HIF. Cancer Cell 2005 8, 91-93DOI: (10.1016/j.ccr.2005.07.012) Copyright © 2005 Elsevier Inc. Terms and Conditions