Fig. 3. Urinary excretion of Na+ and K+ in WNK3 knockout mice Fig. 3. Urinary excretion of Na+ and K+ in WNK3 knockout mice.There were no significant differences in urine volume (A), urinary Na+ excretion (B) or K+ excretion (C) between WNK3 knockout mice (squares, n = 8) and their wild-type littermates (circles, n = 8). Urinary excretion of Na+ and K+ in WNK3 knockout mice.There were no significant differences in urine volume (A), urinary Na+ excretion (B) or K+ excretion (C) between WNK3 knockout mice (squares, n = 8) and their wild-type littermates (circles, n = 8). On day 0, mice were switched from low-salt diet (0.01% NaCl) to high-salt diet (4.0% NaCl). Before switching diet, mice were fed low-salt diet for 1 week. n.s. not significant. Katsuyuki Oi et al. Biology Open 2012;1:120-127 © 2011. Published by The Company of Biologists Ltd