A) Levels of nitrosothiols in breath condensate in normal healthy smokers and patients with chronic obstructive pulmonary disease (COPD). b) Increased.

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a) Levels of nitrosothiols in breath condensate in normal healthy smokers and patients with chronic obstructive pulmonary disease (COPD). b) Increased inducible nitric oxide (iNOS) and nitrotyrosine immunoreactivity in sputum leukocytes in COPD (□) and heal... a) Levels of nitrosothiols in breath condensate in normal healthy smokers and patients with chronic obstructive pulmonary disease (COPD). b) Increased inducible nitric oxide (iNOS) and nitrotyrosine immunoreactivity in sputum leukocytes in COPD (□) and healthy subjects (). *: p<0.05 compared with normal nonsmoking subjects. W. MacNee Eur Respir Rev 2005;14:12-22 ©2005 by European Respiratory Society