P53 tumor suppressor factor, plasminogen activator inhibitor, and vascular endothelial growth factor gene polymorphisms and recurrent implantation failure

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P53 tumor suppressor factor, plasminogen activator inhibitor, and vascular endothelial growth factor gene polymorphisms and recurrent implantation failure Cammi Goodman, M.D., R.S. Jeyendran, D.V.M., Ph.D., C.B. Coulam, M.D. Fertility and Sterility Volume 92, Issue 2, Pages 494-498 (August 2009) DOI: 10.1016/j.fertnstert.2008.07.022 Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Frequency of homozygous mutations for p53 tumor suppressor factor codon Pro72, plasminogen activator inhibitor 1 (PAI-1) 4G/4G, and vascular endothelial growth factor (VEGF) −1154A/A among 70 women with a history of recurrent implantation failure (RIF) compared with 73 fertile control women. Fertility and Sterility 2009 92, 494-498DOI: (10.1016/j.fertnstert.2008.07.022) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Distribution frequency of number of polymorphisms among women experiencing recurrent implantation failure and fertile control women. More than one polymorphism was observed more frequently among women with a history of recurrent implantation failure (RIF) compared with control women (P=.026). Fertility and Sterility 2009 92, 494-498DOI: (10.1016/j.fertnstert.2008.07.022) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions