Cutaneous leishmaniasis in Texas: A northern spread of endemic areas

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Presentation transcript:

Cutaneous leishmaniasis in Texas: A northern spread of endemic areas Natalie A. Wright, BS, Lance E. Davis, BBA, Kent S. Aftergut, MD, Charles A. Parrish, MD, Clay J. Cockerell, MD Journal of the American Academy of Dermatology Volume 58, Issue 4, Pages 650-652 (April 2008) DOI: 10.1016/j.jaad.2007.11.008 Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Black circles: 30 indigenous cases of cutaneous leishmaniasis (CL) reported in south-central Texas since 1903. Red circles: 9 cases of CL concentrated in Dallas-Fort Worth metroplex and surrounding counties. Adopted and modified from Maloney et al.3 Journal of the American Academy of Dermatology 2008 58, 650-652DOI: (10.1016/j.jaad.2007.11.008) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 After 1-week to 3-month incubation period, acute cutaneous leishmaniasis (CL) usually presents with small papule that enlarges into plaque or nodule (A). Over the next number of days, lesions usually ulcerate (B). Ulcerated plaque lesions are characteristic of New World CL. Lesions may involve extremities, although the face is a commonly affected site (C). Biopsy specimens should be taken from organism-dense periphery of lesion to insure most accurate diagnosis. Journal of the American Academy of Dermatology 2008 58, 650-652DOI: (10.1016/j.jaad.2007.11.008) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Cutaneous leishmaniasis is histologically characterized by diffuse infiltrate of plasma cells and histiocytes. Numerous histiocytic intracytoplasmic inclusions represent Leishmania organisms. Distinctly polar appearance of these organisms is attributed to presence of nuclei and kinetoplasts. (Hematoxylin-eosin stain; original magnification: ×60.) Journal of the American Academy of Dermatology 2008 58, 650-652DOI: (10.1016/j.jaad.2007.11.008) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions