Reflex pupillary dilatation in response to skin incision and alfentanil in children anaesthetized with sevoflurane: a more sensitive measure of noxious.

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Reflex pupillary dilatation in response to skin incision and alfentanil in children anaesthetized with sevoflurane: a more sensitive measure of noxious stimulation than the commonly used variables  Constant I. , Nghe M.-C. , Boudet L. , Berniere J. , Schrayer S. , Seeman R. , Murat I.   British Journal of Anaesthesia  Volume 96, Issue 5, Pages 614-619 (May 2006) DOI: 10.1093/bja/ael073 Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 1 Changes in PD and HR measured after skin incision and alfentanil injection at 1 min (group 1, black circles) and 2 min (group 2, grey circles), expressed in percentage of pre-stimulation values [(mean (sd)]. The pupillary size corresponding to each studied point in the two groups, is illustrated on the top portion of the figure. British Journal of Anaesthesia 2006 96, 614-619DOI: (10.1093/bja/ael073) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 2 In all children (n=24), individual values of PD, HR, SBP and BIS, measured at baseline (♦) and 60 s after skin incision (), and plotted against age. British Journal of Anaesthesia 2006 96, 614-619DOI: (10.1093/bja/ael073) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 3 PD and HR in prepubertal children (n=12) compared with pubertal children (n=12) measured in the first minute after skin incision [mean (sd)]. **P<0.01, ***P<0.001, prepubertal vs pubertal children. British Journal of Anaesthesia 2006 96, 614-619DOI: (10.1093/bja/ael073) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

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