Microbiological and Physicochemical Stability of Oxycodone Hydrochloride Solutions for Patient-Controlled Delivery Systems Ahmed Amri, PharmD, Ahmed.

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Microbiological and Physicochemical Stability of Oxycodone Hydrochloride Solutions for Patient-Controlled Delivery Systems Ahmed Amri, PharmD, Ahmed Ben Achour, PharmD, Elisabeth Chachaty, PharmD, PhD, Lionel Mercier, Philippe Bourget, PharmD, PhD, Angelo Paci, PharmD, PhD Journal of Pain and Symptom Management Volume 40, Issue 1, Pages 87-94 (July 2010) DOI: 10.1016/j.jpainsymman.2009.11.323 Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Chemical structure of oxycodone. Journal of Pain and Symptom Management 2010 40, 87-94DOI: (10.1016/j.jpainsymman.2009.11.323) Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Chromatogram of oxycodone solution after 28 days of storage at room temperature (15–25°C). Journal of Pain and Symptom Management 2010 40, 87-94DOI: (10.1016/j.jpainsymman.2009.11.323) Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions