Starvation triggers the induction of FAM134B-2 in liver and other peripheral tissue. Starvation triggers the induction of FAM134B-2 in liver and other peripheral tissue. (A) Schematic models of human FAM134B-1 and FAM134B-2 genes. (B) Membrane topology model generated by Protter for human and mouse FAM134B-2. Red indicates the LC3-interacting region (LIR). (C) Gel electrophoresis of RT-PCR product of mouse brain and fasted liver using FAM134B-1 or FAM134B-2 specific primers. (D) Immunoblot analysis of FAM134B in brain, kidney, spleen and white adipose tissue from fed or 16-h fasted mice. Shohei Kohno et al. LSA 2019;2:e201900340 © 2019 Kohno et al.