Effects of streptozotocin treatment on several kinases that can phosphorylate tau. Effects of streptozotocin treatment on several kinases that can phosphorylate.

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Effects of streptozotocin treatment on several kinases that can phosphorylate tau. Effects of streptozotocin treatment on several kinases that can phosphorylate tau. Mice were treated with streptozotocin (S), and after 3 days, cerebral cortex protein extracts were immunoblotted for phospho–Ser9-GSK3β, total GSK3β, Cdk5 (p35 and p25 catalytic subunits), phospho–Thr202,Tyr204-ERK1/2, total ERK1/2, phospho–Thr180,Tyr182-p38, total p-38, phospho–Thr183,Tyr185-JNK, and total JNK. C, control; S, streptozotocin treated. Buffie J. Clodfelder-Miller et al. Diabetes 2006;55:3320-3325 ©2006 by American Diabetes Association