Fig. 1 ZIKV RNA in blood and tissues.

Slides:



Advertisements
Similar presentations
Demonstrations I, II, and III.
Advertisements

Self-folding triangular devices at two scales.
Three different types of transfer functions with a codomain of [0,1].
Robot surface tension experiments.
Regulatory CD4+ T cell–derived IL-10 is important for B cell differentiation and the GC response. Regulatory CD4+ T cell–derived IL-10 is important for.
CD169+ macrophages mediate Lm translocation to the splenic T cell zones. CD169+ macrophages mediate Lm translocation to the splenic T cell zones. (A) Confocal.
Examples of AEGIS autonomous target selection.
TCR signaling induces nuclear actin polymerization.
Demonstration of aerial-aquatic locomotion and transition.
Robot design, component fabrication, and assembly.
Altered distribution of γδT IELs in GPR55-deficient mice.
Tukey boxplots overlaid on data points from objective and subjective measures, displaying results from study 1. Tukey boxplots overlaid on data points.
Fig. 7 Correlation of NHP and human ISGs.
Erythroid differentiation of human CD34+ cells promoted by AVP
Fig. 1 Movement percepts for all participants.
The milliDelta: a millimeter-scale Delta robot.
Fig. 5 Quantitative assessment of the efficacy of the tissue-engineered implant to heal the TMJ disc defect. Quantitative assessment of the efficacy of.
NRP1-expressing macrophages accumulate in adipose tissue during DIO and regulate weight gain and glucose tolerance. NRP1-expressing macrophages accumulate.
Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.
Cell viability tests. Cell viability tests. SEM images of (A) MC3T3-E1 cells and (B) MSCs on days 1, 3, and 5 of culture. (C) Survival rates of MC3T3-E1.
Fig. 7 Bacterial dependency networks in IgA deficiency and HDs.
Effect of slenderness on optimal shapes.
Fig. 3 ROC curves of mCCNA1 and mVIM assayed in esophageal cytology brushings from control normal-appearing GE junctions versus BE and EAC cases. ROC curves.
CD169+ macrophages mediate the transport of bacteria to T cell zones by trans-infecting CD8α+ DCs. CD169+ macrophages mediate the transport of bacteria.
Fig. 2 Preserved long-term functionality of the TEHVs over 1-year follow-up as assessed by ICE and cardiac MRI flow measurements. Preserved long-term functionality.
Fig. 1 Pump-probe signatures of vermilion (red HgS), black HgS, and metallic Hg. Pump-probe signatures of vermilion (red HgS), black HgS, and metallic.
In vivo release of doxycycline hyclate from the GRS in a swine model
Genetic EGFR ablation in K-RAS–mutated lung AC reduces tumor growth
CD25 expression identifies two transcriptionally distinct subsets of very early effector cells. CD25 expression identifies two transcriptionally distinct.
Pollen tube guidance in flowering plants.
Fig. 5. Immunohistochemistry of the tumor microenvironment in GBM specimens before and after CART-EGFRvIII infusion. Immunohistochemistry of the tumor.
Characterization of the MCs.
Fig. 2 Activation of LRRK2 kinase in nigrostriatal dopamine neurons in human iPD postmortem brain tissue. Activation of LRRK2 kinase in nigrostriatal dopamine.
Object manipulations performed by our biohybrid robots.
STARmap for 3D transcriptome imaging and molecular cell typing.
Fig. 6 WPS imaging of different chemical components in living cells.
Galloping-like gait with the design of a two-legged robot.
AEGIS autonomous targeting process.
Examples of AEGIS autonomous target selection.
Fig. 3 Local Maraba treatment of TNBC tumors provides long-term systemic protection. Local Maraba treatment of TNBC tumors provides long-term systemic.
Fig. 4. Paclitaxel promotes the expression of invasive isoforms of MENA in the primary breast cancer microenvironment. Paclitaxel promotes the expression.
Ifnar1+/− placentas show increased apoptosis and abnormal maternal-fetal blood barrier. Ifnar1+/− placentas show increased apoptosis and abnormal maternal-fetal.
Representative CT and PET/CT images of three patients with NSCLCs
Fig. 1 Deficient CD73 and CD39 expressions and extracellular adenosine concentration in BM of OVX animals. Deficient CD73 and CD39 expressions and extracellular.
Fig. 2 Effect of CSF sTREM2– and CSF sTREM2–to–p-tau181 ratio on changes in cognition. Effect of CSF sTREM2– and CSF sTREM2–to–p-tau181 ratio on changes.
Fig. 5. Vascularization of human liver seed grafts.
Tissue architecture affects function of expanded liver seed grafts
Fig. 2 Neonatal ZIKV infection induces seizures in young mice and increases susceptibility to chemically induced seizures in adult mice. Neonatal ZIKV.
Fig. 6 Antitumor effect on tumor growth and pulmonary metastasis of CSSD-9 in vivo. Antitumor effect on tumor growth and pulmonary metastasis of CSSD-9.
Fig. 3 Viral loads and viral DNA in anti-α4β7 antibody–treated rhesus macaques that initiated ART during chronic SIVmac251 infection (study 2). Viral loads.
Fig. 1 Study design and antibody pharmacokinetics.
Fig. 2 Increasing KLF17, CDH1, and LASS2 expression reduced malignant progression and promoted apoptosis of tumor cells. Increasing KLF17, CDH1, and LASS2.
Fig. 1 Undetectable ALK expression in monocytes and macrophages.
Fig. 5. High burdens of AA signature mutations and predicted immunogenicity in Taiwan HCCs. High burdens of AA signature mutations and predicted immunogenicity.
Fig. 2 RVFV causes pathology within the liver, uterus, and placenta of pregnant dams. RVFV causes pathology within the liver, uterus, and placenta of pregnant.
Fig. 1. Construction of human liver seed grafts.
Fig. 7 BEL immune response.
Fig. 4 Single-particle contact angle measurements.
Fig. 5 LASV replication in cynomolgus monkeys.
Fig. 2 Supraballs and films from binary SPs.
Fig. 1 B2 RNA directly inhibits transcription.
Fig. 4 Gallium increases P. aeruginosa sensitivity to peroxides.
Fig. 8 Immune correlates of protection.
Fig. 5. Paclitaxel promotes breast cancer cell dissemination and metastasis in a MENA-dependent manner. Paclitaxel promotes breast cancer cell dissemination.
The neuropod cells. The neuropod cells. (Top left) Neuropod cells synapse with sensory neurons in the small intestine, as shown in a confocal microscopy.
Neutralizing activity of mAbs isolated from plasmablasts during acute ZIKV infection in DENV-experienced donors. Neutralizing activity of mAbs isolated.
Fig. 1 CPCB-RPE1 investigational implant.
Fig. 2 Imaging blood vessel before and after closure.
Fig. 3 4n hybrids undergo bipolar and tripolar mitosis.
Fig. 2 Astrocyte-specific AAV2/5 RiboTag.
Presentation transcript:

Fig. 1 ZIKV RNA in blood and tissues. ZIKV RNA in blood and tissues. (A) Plasma ZIKV RNA concentration as measured by RT-PCR. (B) Assessment of ZIKV RNA concentration by RT-PCR in lymphoid (top) and nonlymphoid tissues (bottom) at day 3 or days 14 and 15 post-infection (p.i.). Low RNA indicates that <20 ng/μl was run in the PCR. LN, lymph node. (C) Representative detection of ZIKV RNA by RNAscope in situ hybridization in nervous system tissues. Arrowheads indicate some of the most intense RNAscope signals (red). No arrowheads were placed on the bottom left panel because the RNAscope signal was diffusely positive in the cerebellum at this magnification. Scale bars, 100 μm (left panels) and 50 μm (right panels). Four to five images per brain area were examined. Maud Mavigner et al., Sci Transl Med 2018;10:eaao6975 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works