Dyspnea on Exertion and Ground-Glass Infiltrates in an Ex-Smoker

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Dyspnea on Exertion and Ground-Glass Infiltrates in an Ex-Smoker Mohit Chawla, MD, Nahal Boroumand, MD, Constantinos Alexandrou, MD, Diane Stover, MD, FCCP CHEST Volume 134, Issue 6, Pages 1320-1324 (December 2008) DOI: 10.1378/chest.07-2119 Copyright © 2008 The American College of Chest Physicians Terms and Conditions

Figure 1 CT of the chest without contrast (7.5-mm sections; our initial scan after a course of clarithromycin) showing poorly defined areas of GGA predominantly in bilateral posterior segments of upper lobes and superior segments of lower lobes. CHEST 2008 134, 1320-1324DOI: (10.1378/chest.07-2119) Copyright © 2008 The American College of Chest Physicians Terms and Conditions

Figure 2 CT of the chest without contrast (7.5-mm sections; our initial scan after a course of clarithromycin) showing poorly defined areas of GGA predominantly in bilateral posterior segments of upper lobes and superior segments of lower lobes. CHEST 2008 134, 1320-1324DOI: (10.1378/chest.07-2119) Copyright © 2008 The American College of Chest Physicians Terms and Conditions

Figure 3 Left lower lobe, superior segment, including alveolar septa (single arrow), foamy macrophages within alveolar septum (opposing double arrows), and intraaalveolar macrophages (double arrows) [hematoxylin-eosin, original × 20]. CHEST 2008 134, 1320-1324DOI: (10.1378/chest.07-2119) Copyright © 2008 The American College of Chest Physicians Terms and Conditions

Figure 4 Left lower lobe, superior segment, again showing intraaalveolar macrophages (hematoxylin-eosin, original × 40). CHEST 2008 134, 1320-1324DOI: (10.1378/chest.07-2119) Copyright © 2008 The American College of Chest Physicians Terms and Conditions