Microbial differences found between TPC- and PBS-treated mice with lupus. Microbial differences found between TPC- and PBS-treated mice with lupus. (A)

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Microbial differences found between TPC- and PBS-treated mice with lupus. Microbial differences found between TPC- and PBS-treated mice with lupus. (A) Bar chart of significant differences in gut bacterial abundances between TPC- and PBS-treated mice with lupus at day 35 based on LEfSe analysis. (B) Heatmap of differential features correlated with protein levels in TPC- versus PBS-treated mice with lupus at day 35, generated using Calour. Bacteria were selected using Pearson's correlation with a dsFDR of 0.05 multiple hypothesis correction. Top color bars (TPC/PBS) indicate the different treatments. Side color bar indicates relative reads out of 10,000 (following normalization of each sample to 10,000 reads). (C) Bar chart of significant differences in predicted gut bacterial function between TPC- and PBS-treated mice with lupus at day 35 based on PICRUSt analysis. Hadar Neuman et al. mSystems 2019; doi:10.1128/mSystems.00160-18