Baroreflex impairment and morbidity after major surgery

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Presentation transcript:

Baroreflex impairment and morbidity after major surgery A. Toner, N. Jenkins, G.L. Ackland British Journal of Anaesthesia Volume 117, Issue 3, Pages 324-331 (September 2016) DOI: 10.1093/bja/aew257 Copyright © 2016 The Author(s) Terms and Conditions

Fig 1 Baroreflex analysis and hospital stay. (a) Schematic diagram showing measurement and calculation of baroreflex sensitivity (BRS). Using a validated sequence method technique (one beat lag), a baroreflex event is defined by three or more consecutive beats where the systolic blood pressure (SBP) and pulse interval (PI) changed in tandem and are highly correlated (r>0.85). (b) The slope of the linear regression line of PI against SBP generates the BRS of each event in milliseconds per millimetre of mercury. (b) Baroreflex sensitivity <6 ms mm Hg−1 was associated with prolonged hospital stay [hazard ratio:1.62 (95% confidence interval: 1.14–2.32); P=0.004; unadjusted log-rank analysis]. Inset plot highlights length of stay in patients with BRS <3 ms mm Hg−1. British Journal of Anaesthesia 2016 117, 324-331DOI: (10.1093/bja/aew257) Copyright © 2016 The Author(s) Terms and Conditions