Top panel: AUC0–31h of M1 and glargine in the nine individual subjects (M1, open circles; glargine, filled circles) and median and 10th, 25th, 75th, and.

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Top panel: AUC0–31h of M1 and glargine in the nine individual subjects (M1, open circles; glargine, filled circles) and median and 10th, 25th, 75th, and 90th percentiles AUC0–31h in the group of M1 (open box) and glargine (hatched box) (top left panel) and Cmax of M1 (open circles) and glargine (filled circles) in individual subjects and median and 10th, 25th, 75th, and 90th percentiles Cmax in the group of M1 (open box) and glargine (hatched box) (top right panel). Top panel: AUC0–31h of M1 and glargine in the nine individual subjects (M1, open circles; glargine, filled circles) and median and 10th, 25th, 75th, and 90th percentiles AUC0–31h in the group of M1 (open box) and glargine (hatched box) (top left panel) and Cmax of M1 (open circles) and glargine (filled circles) in individual subjects and median and 10th, 25th, 75th, and 90th percentiles Cmax in the group of M1 (open box) and glargine (hatched box) (top right panel). Bottom panel: individual values of AUC0–31h of M1 and glargine (LC-MS/MS) (bottom left panel) and Cmax of M1 and glargine (M1 open columns; glargine, hatched columns) in the nine subjects. Paola Lucidi et al. Dia Care 2012;35:2647-2649 ©2012 by American Diabetes Association