A randomized, double-blind, placebo-controlled pilot trial of triiodothyronine in neonatal heart surgery Andrew S. Mackie, MD, SM, Karen L. Booth, MD,

Slides:

Advertisements

Similar presentations

Max B. Mitchell, MD The Journal of Thoracic and Cardiovascular Surgery

Advertisements

Lost in translation The Journal of Thoracic and Cardiovascular Surgery

Manuel J. Antunes, MD, PhD, DSc

Stephen R. Broderick, MD, MPHS

Stage I Norwood: Optimal technical performance improves outcomes irrespective of preoperative physiologic status or case complexity John M. Karamichalis,

Extracorporeal membrane oxygenation support of the Fontan and bidirectional Glenn circulations Karen L Booth, MD, Stephen J Roth, MD,MPH, Ravi R Thiagarajan,

Kathy J. Jenkins, MD, MPH, Kimberlee Gauvreau, ScD, Jane W

Surgery for coarctation of the aorta in infants weighing less than 2 kg Emile A Bacha, MD, Melvin Almodovar, MD, David L Wessel, MD, David Zurakowski,

The days of future past Neel K. Ranganath, MD, Aubrey C. Galloway, MD

Outcomes of surgery for young children with multivessel pulmonary vein stenosis Luis G. Quinonez, MD, Kimberlee Gauvreau, PhD, Michele Borisuk, NP, Christina.

The effect of hematocrit during hypothermic cardiopulmonary bypass in infant heart surgery: Results from the combined Boston hematocrit trials David.

Centers for Disease Control “increased-risk” organ donor: Not so risky? Francis D. Pagani, MD, PhD The Journal of Thoracic and Cardiovascular Surgery

Form ever follows function

William M. DeCampli, MD, PhD

Application of a neuroscience research model to study neuroprotection in children with congenital heart disease Nobuyuki Ishibashi, MD, Richard A. Jonas,

Definition of postoperative bleeding in children undergoing cardiac surgery with cardiopulmonary bypass: One size doesn't fit all David Faraoni, MD,

Early repair of hemitruncus: Excellent early and late outcomes

The lord of the rings Antonio Miceli, MD, PhD

Technical Performance Scores are strongly associated with early mortality, postoperative adverse events, and intensive care unit length of stay—analysis.

Historical perspectives of The American Association for Thoracic Surgery: George P. Muller, MD, ScD ( ) Richard N. Edie, MD The Journal of Thoracic.

Intermediate-term results of repair for aortic, neoaortic, and truncal valve insufficiency in children John A. Hawkins, MD, Peter C. Kouretas, MD, PhD,

Aldo R. Castañeda, MD, PhD: Recipient of the Lifetime Achievement Award and 74th president of The American Association for Thoracic Surgery Pedro J.

Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery Jane W. Newburger, MD, MPH, Richard A.

Juan N. Pulido, MD The Journal of Thoracic and Cardiovascular Surgery

Clinical outcome score predicts the need for neurodevelopmental intervention after infant heart surgery Andrew S. Mackie, MD, SM, Gwen Y. Alton, RN,

Innovation and science: The future of valve design

The assessment of cost effectiveness and the effectiveness of cost assessment in cardiothoracic surgery Vinay Badhwar, MD The Journal of Thoracic and.

It's not “just a shunt” but sometimes it should be…

Fixing the supply problem

Military surgeons just want to have fun

Historical perspectives of The American Association for Thoracic Surgery: Pedro J. del Nido John R. Spratt, MD, MA, Kristine J. Guleserian, MD, Sara.

Do we need a bibliometrician to know which way the wind is blowing?

A first start for lung transplantation?

The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants Richard A Jonas, MD, David.

Confusion still exists regarding postoperative delirium and its etiology after esophagectomy Robert B. Cameron, MD The Journal of Thoracic and Cardiovascular.

Niv Ad, MD, Sari D. Holmes, PhD, Paul S. Massimiano, MD, Anthony J

Stephen R. Broderick, MD, MPHS

Effect of hydroxyethyl starch on bleeding after cardiopulmonary bypass: A meta-analysis of randomized trials Roberta J. Navickis, PhD, Gary R. Haynes,

Joseph A. Dearani, MD, Michael J. Ackerman, MD, PhD

Commentary: Faster recovery after complex neonatal cardiac surgery

Jeevanantham Rajeswaran, PhD, Eugene H. Blackstone, MD

Replicating the success of mitral valve repair in the aortic valve

Frank C. Spencer, MD, FACS, pioneering cardiothoracic surgeon

Video-assisted resection for lung cancer results in fewer complications Lunxu Liu, PhD, MD, FRCS The Journal of Thoracic and Cardiovascular Surgery

National Institutes of Health funding for cardiothoracic surgical research Mark B. Ratcliffe, MD, Cheryl Howard, MPH, Michael Mann, MD, Pedro del Nido,

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

James I. Fann, MD, John E. Connolly, MD

Long-term results of the lateral tunnel Fontan operation

Meta-analysis of randomized trials on the efficacy of posterior pericardiotomy in preventing atrial fibrillation after coronary artery bypass surgery

The origins of open heart surgery at the University of Minnesota 1951 to 1956 Richard A. DeWall, MD The Journal of Thoracic and Cardiovascular Surgery

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

Valved homograft conduit repair of the right heart in early infancy

The future of cardiac surgery training: A survival guide

Hope should not spring eternal

The continuing challenge of congenital heart disease in China

Outcome after repair of atrioventricular septal defect with tetralogy of Fallot Jeffrey H. Shuhaiber, MD, Barbara Robinson, MD, Kimberlee Gauvreau, ScD,

Seeing is believing: A call for routine early postoperative hemodynamic transesophageal echocardiography monitoring after left ventricular assist device.

“The more things change…”: The challenges ahead

Managing conflicts of interest

First in line for robotic surgery: Would you want to know?

Ryan R. Davies, MD The Journal of Thoracic and Cardiovascular Surgery

More than vital: Who bears the burden?

Lung cancer randomized controlled trials should compare stereotactic body radiation therapy with observation, NOT surgery Raja M. Flores, MD The Journal.

Did you like Terminator 3 better than Terminator 2

A good chimney requires a good sweep

Successful implantation of a Berlin heart biventricular assist device in a failing single ventricle Meena Nathan, MD, Christopher Baird, MD, Francis.

Journal changes and initiatives

Zone zero thoracic endovascular aortic repair is all about “location, location, location” Kevin L. Greason, MD The Journal of Thoracic and Cardiovascular.

Calpain inhibitors: The aspirin of the 21st century?

Presentation transcript:

A randomized, double-blind, placebo-controlled pilot trial of triiodothyronine in neonatal heart surgery Andrew S. Mackie, MD, SM, Karen L. Booth, MD, Jane W. Newburger, MD, MPH, Kimberlee Gauvreau, ScD, Stephen A. Huang, MD, Peter C. Laussen, MBBS, James A. DiNardo, MD, Pedro J. del Nido, MD, PhD, John E. Mayer, MD, Richard A. Jonas, MD, Ellen McGrath, RN, Jodi Elder, RN, Stephen J. Roth, MD, MPH The Journal of Thoracic and Cardiovascular Surgery Volume 130, Issue 3, Pages 810-816 (September 2005) DOI: 10.1016/j.jtcvs.2005.04.025 Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 T3 levels measured in the operating room before and after CPB and at 24, 48, and 72 postoperative hours and 7 and 14 postoperative days. Error bars represent 95% confidence intervals. Shaded zones indicate normal ranges (Nichols Institute, San Juan Capistrano, Calif). Total T3 levels (A) and free T3 levels (B) were higher in the T3 group at 24, 48, and 72 postoperative hours (P < .001). The Journal of Thoracic and Cardiovascular Surgery 2005 130, 810-816DOI: (10.1016/j.jtcvs.2005.04.025) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Systolic blood pressure (A) was higher in the T3 group (P < .001) during the early postoperative period, as was mean blood pressure (B) (P = .02). Error bars represent 95% confidence intervals. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 810-816DOI: (10.1016/j.jtcvs.2005.04.025) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions