Effect of palmitate and oleate preincubation on fatty acid oxidation, triglyceride content, glycerol release, and HSL mRNA. Effect of palmitate and oleate.

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Effect of palmitate and oleate preincubation on fatty acid oxidation, triglyceride content, glycerol release, and HSL mRNA. Effect of palmitate and oleate preincubation on fatty acid oxidation, triglyceride content, glycerol release, and HSL mRNA. Wild-type and +CD36 myotubes were preincubated for 36 h with 750 μmol/l palmitate (A) or 750 μmol/l oleate (B), washed, and assayed for fatty acid uptake and oxidation and for triglyceride content and glycerol release as described for Figs. 1 and 2. Data are means ± SD of triplicates from four different experiments. *P < 0.05. HSL mRNA abundance was determined by RT-PCR. Data are means ± SD from two separate experiments with triplicate determinations. Claire C. Bastie et al. Diabetes 2004;53:2209-2216 ©2004 by American Diabetes Association