Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and.

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Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and progression of knee osteoarthritis: a 3-year follow-up of the ROAD study  N. Yoshimura, S. Muraki, H. Oka, S. Tanaka, H. Kawaguchi, K. Nakamura, T. Akune  Osteoarthritis and Cartilage  Volume 20, Issue 11, Pages 1217-1226 (November 2012) DOI: 10.1016/j.joca.2012.06.006 Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Flow of participants in the baseline and second surveys. Osteoarthritis and Cartilage 2012 20, 1217-1226DOI: (10.1016/j.joca.2012.06.006) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Cumulative incidence (%/year) of KOA (A) and progression of the KL grade of either knee (%/year) (B) classified by the number of components of MS, including OW, HT, DL, and IGT. Osteoarthritis and Cartilage 2012 20, 1217-1226DOI: (10.1016/j.joca.2012.06.006) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 ORs for occurrence and progression of KOA during the 3-year follow-up period vs the number of risk factors for MS. Osteoarthritis and Cartilage 2012 20, 1217-1226DOI: (10.1016/j.joca.2012.06.006) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions