Hiral P. Fontanilla, MD, Ann H. Klopp, MD, PhD, Mary E

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Date of download: 5/28/2016 Copyright © The American College of Cardiology. All rights reserved. From: Coronary Flow Reserve and Pharmacologic Stress Perfusion.

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Anatomic distribution of [18F] fluorodeoxyglucose-avid lymph nodes in patients with cervical cancer Hiral P. Fontanilla, MD, Ann H. Klopp, MD, PhD, Mary E. Lindberg, BS, Anuja Jhingran, MD, Patrick Kelly, MD, PhD, Vinita Takiar, MD, PhD, Revathy B. Iyer, MD, Charles F. Levenback, MD, Yongbin Zhang, PhD, Lei Dong, PhD, Patricia J. Eifel, MD Practical Radiation Oncology Volume 3, Issue 1, Pages 45-53 (January 2013) DOI: 10.1016/j.prro.2012.02.003 Copyright © 2013 American Society for Radiation Oncology Terms and Conditions

Figure 1 “Atlas” of positron emission tomography (PET)-positive LNs. Representative axial images (superior to inferior) showing the location of all 190 identified PET-positive lymph nodes. All nodes from each patient are contoured in the same color; each color isused for 2 patients. Practical Radiation Oncology 2013 3, 45-53DOI: (10.1016/j.prro.2012.02.003) Copyright © 2013 American Society for Radiation Oncology Terms and Conditions

Figure 2 Anatomic distribution of positron emission tomography-positive lymph nodes (LN) based on a volume probability map. A color gradient corresponding to the visible-light spectrum is used to indicate the frequency of LN involvement. (Red, high frequency; green, moderate frequency; blue, low frequency.) Practical Radiation Oncology 2013 3, 45-53DOI: (10.1016/j.prro.2012.02.003) Copyright © 2013 American Society for Radiation Oncology Terms and Conditions

Figure 3 Coverage of (PET)-positive lymph nodes (LNs) by conventional treatment fields. Anterior-posterior (left panel) and lateral (right panel) views show conventional pelvic radiation therapy fields used in cervical cancer treatment, with the superior border at the L4/L5 interspace. PET-positive LNs (n = 190) are shown as 1-cm-diameter spheres expanding from the center of the original node. Practical Radiation Oncology 2013 3, 45-53DOI: (10.1016/j.prro.2012.02.003) Copyright © 2013 American Society for Radiation Oncology Terms and Conditions

Figure 4 Representative axial images showing coverage of positron emission tomographic (PET)-positive lymph nodes (LNs) when the nodal target volume is contoured according to Radiation Therapy Oncology Group consensus guidelines (yellow). Majority of PET-positive LNs were adequately covered. Generous coverage is required in areas of high frequency of nodal involvement, including common iliac nodes anterior to the psoas muscle (solid white arrow), posteriorly between psoas and sacrum (open white arrow), and external iliac nodes (thin black arrow). Lymph nodes inferior to the contours were not covered (lower right image). Practical Radiation Oncology 2013 3, 45-53DOI: (10.1016/j.prro.2012.02.003) Copyright © 2013 American Society for Radiation Oncology Terms and Conditions

Supplementary Material (JPEG) Figure e1 Practical Radiation Oncology 2013 3, 45-53DOI: (10.1016/j.prro.2012.02.003) Copyright © 2013 American Society for Radiation Oncology Terms and Conditions