Effects of delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in marijuana, on human sperm function in vitro Lynne B. Whan, Ph.D., Mhairi.

Slides:

Advertisements

Similar presentations

What’s the delay? A qualitative study of women’s experiences of reaching a diagnosis of endometriosis Karen Ballard, Ph.D., Karen Lowton, Ph.D., Jeremy.

Advertisements

Effect of vaginal lubricants on sperm motility and chromatin integrity: a prospective comparative study Ashok Agarwal, Ph.D., Fnu Deepinder, M.D., Marcello.

Who requests their sperm donor's identity

Daily physical activity and hot flashes in the Study of Women's Health Across the Nation (SWAN) Flashes Study Carolyn Gibson, M.P.H., M.S., Karen Matthews,

The great debate: varicocele treatment and impact on fertility

Fertility and Sterility Volume 97, Issue 3, Pages (March 2012)

The relative effects of hormones and relationship factors on sexual function of women through the natural menopausal transition Lorraine Dennerstein,

Comparison of Sperm Motility Measurement Using SQA-V Automated Sperm Analyzer and Conventional Manual Methods R.K. Sharma, T.M. Said, A. Agarwal Fertility.

Ranjit S. Sandhu, B. S. , Timothy H. Wong, B. A. , Crystal A. Kling, B

The normal variabilities of the menstrual cycle

Fernando Zegers-Hochschild, M.D. Fertility and Sterility

Nabil Aziz, M. D. , Ashok Agarwal, Ph. D. , HCLD, Iwan Lewis-Jones, M

Michael M. Alper, M.D. Fertility and Sterility

Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and in vitro fertilization success Luke Simon,

A short period of ejaculatory abstinence before intrauterine insemination is associated with higher pregnancy rates Paul B. Marshburn, M.D., Mark Alanis,

Dennis J. Hand, Ph. D. , Vanessa L. Short, Ph. D. , M. P. H. , Diane J

Hepatitis and reproduction

Contrasting patterns in in vitro fertilization pregnancy rates among fresh autologous, fresh oocyte donor, and cryopreserved cycles with the use of day.

Robot-assisted laparoscopy for infertility treatment: current views

Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study Nicole Hope, M.B., B.S., Hon., Luk.

Comparison of fallopian tube sperm perfusion and intrauterine tuboperitoneal insemination: a prospective randomized study Leonidas Mamas, M.D., Ph.D.

Azoospermia: is sample centrifugation indicated

Computer-assisted motility analysis of spermatozoa obtained after spermatogonial stem cell transplantation in the mouse Ellen Goossens, Ph.D., Gert De.

Medical treatment of ectopic pregnancy: a committee opinion

The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society.

Live birth of twins derived from zona-free oocytes

Ahmad Majzoub, M. D. , Nicholas N. Tadros, M. D. , A

How old is too old? Challenges faced by clinicians concerning age cutoffs for patients undergoing in vitro fertilization Robert L. Klitzman, M.D. Fertility.

Fertility and Sterility

Oocyte cryopreservation

Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa

Mieke Carine Wim Eeckhaut, Ph.D. Fertility and Sterility

Looking back: egg donors' retrospective evaluations of their motivations, expectations, and experiences during their first donation cycle Nancy J. Kenney,

A comparison of three downregulation approaches for poor responders undergoing in vitro fertilization Laura Detti, M.D., Daniel B. Williams, M.D., Jared.

Sperm deoxyribonucleic acid damage in normozoospermic men is related to age and sperm progressive motility Stephanie Belloc, Pharm.D., Moncef Benkhalifa,

Management of tubal ectopic pregnancy: methotrexate and salpingostomy are preferred to preserve fertility Stephanie Beall, M.D., Ph.D., Alan H. DeCherney,

Clomiphene citrate at 50: the dawning of assisted reproduction

David R. J. Glenn, M. R. C. O. G. , Neil McClure, F. R. C. O. G. , S

Introduction Fertility and Sterility

What is the best frame rate for evaluation of sperm motility in different species by computer-assisted sperm analysis? Cesare Castellini, Ph.D., Alessandro.

Akanksha Mehta, M.D., Darius A. Paduch, M.D., Ph.D.

Evaluation of diagnostic testis biopsy and the repetition of testicular sperm extraction surgeries in infertility patients Alayman Hussein, M.B.B.C.H.,

Number of good quality embryos on day 3 is predictive for both pregnancy and implantation rates in in vitro fertilization/intracytoplasmic sperm injection.

Birth outcomes after spontaneous or assisted conception among infertile Australian women aged 28 to 36 years: a prospective, population-based study Danielle.

Molecular aspects of declining sperm motility in older men

A longitudinal study of the effects of free testosterone and other psychosocial variables on sexual function during the natural traverse of menopause

Fertility and Sterility

P-425 Fertility and Sterility Volume 86, Issue 3, (September 2006)

Website quality assessment: Mistaking apples for oranges

Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.

L. Scott, J. Bernsten, K. DeLegge, J. Hill, N. Ramsing

Reducing the dose of human chorionic gonadotropin in high responders does not affect the outcomes of in vitro fertilization David W. Schmidt, M.D.,,

Fertility and Sterility: an evaluation

Insulin growth factors may be implicated in human sperm capacitation

Eric S. Surrey, M. D. , Debra A. Minjarez, M. D. , John M. Stevens, B

Current evaluation of amenorrhea

Genetic evaluation procedures at sperm banks in the United States

Reduced sperm yield from testicular biopsies of vasectomized men is due to increased apoptosis Deirdre A. O’Neill, M.Sc., Carmel M. McVicar, Ph,D., Neil.

Follicular fluid of single follicles from women with PCOS contains higher levels of müllerian inhibiting substance L.T. Ku, S.T. Nakajima, M.E. McClure,

Marcia E. Garcez, M. Sc. , Cátia dos Santos Branco, M. Sc

Egg production predicts a doubling of in vitro fertilization pregnancy rates even within defined age and ovarian reserve categories Melissa C. Yih, M.D.,

In vitro sildenafil citrate use as a sperm motility stimulant

Saad Elzanaty, M.D., Ph.D., Johan Malm, M.D., Ph.D.

Cumulative live birth rates in cohorts of patients treated with in vitro fertilization or intracytoplasmic sperm injection Cynthia Witsenburg, M.D.,

Decreased sperm motility is associated with air pollution in Salt Lake City Ahmad Hammoud, M.D., M.P.H., Douglass T. Carrell, Ph.D., H.C.L.D., Mark Gibson,

What’s the delay? A qualitative study of women’s experiences of reaching a diagnosis of endometriosis Karen Ballard, Ph.D., Karen Lowton, Ph.D., Jeremy.

Are sperm DNA fragmentation, hyperactivation, and hyaluronan-binding ability predictive for fertilization and embryo development in in vitro fertilization.

Contact among families who share the same sperm donor

David R. J. Glenn, M. R. C. O. G. , Carmel M. McVicar, Ph. D

Numerical chromosome anomalies detected in paternally derived pronuclei of tripronuclear zygotes after intracytoplasmic sperm injection Ervin Macas,

Presentation transcript:

Effects of delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in marijuana, on human sperm function in vitro Lynne B. Whan, Ph.D., Mhairi C.L. West, Ph.D., Neil McClure, M.R.C.O.G., Sheena E.M. Lewis, Ph.D. Fertility and Sterility Volume 85, Issue 3, Pages 653-660 (March 2006) DOI: 10.1016/j.fertnstert.2005.08.027 Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 (A) Effect of THC, at recreational and therapeutic concentrations, on the numbers of progressively motile sperm in the 90% fraction. (B) Effect of THC, at recreational and therapeutic concentrations, on the numbers of progressively motile sperm in the 45% fraction. Black bar = control; yellow bar = 0.032 μM; red bar = 0.32 μM; blue bar = 4.8 μM THC. Whan. Cannabis and sperm function. Fertil Steril 2006. Fertility and Sterility 2006 85, 653-660DOI: (10.1016/j.fertnstert.2005.08.027) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 2 Effect of THC, at the higher therapeutic concentration, on the quality of sperm motility (VAP and VSL) in the 90% fraction. Black bar = control; blue bar = 4.8 μM THC. Whan. Cannabis and sperm function. Fertil Steril 2006. Fertility and Sterility 2006 85, 653-660DOI: (10.1016/j.fertnstert.2005.08.027) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 3 (A) Effect of THC, at recreational and therapeutic concentrations, on the acrosome reaction of sperm in the 90% fraction. (B) Effect of THC, at recreational and therapeutic concentrations, on the acrosome reaction of sperm in the 45% fraction. Black bar = control; yellow bar = 0.032 μM; red bar = 0.32 μM; blue bar = 4.8 μM THC. Whan. Cannabis and sperm function. Fertil Steril 2006. Fertility and Sterility 2006 85, 653-660DOI: (10.1016/j.fertnstert.2005.08.027) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 4 Effect of THC, at the higher recreational concentration, on the artificially induced acrosome reaction of sperm in the 90% fraction. Whan. Cannabis and sperm function. Fertil Steril 2006. Fertility and Sterility 2006 85, 653-660DOI: (10.1016/j.fertnstert.2005.08.027) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions