Fig. 10. Expression of the cholinergic receptor subunits Chrna6 and Chrnb3 depends on Pitx3.In situ hybridization for Th, Chrna6 and Chrnb3 on sagittal.

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Fig. 10. Expression of the cholinergic receptor subunits Chrna6 and Chrnb3 depends on Pitx3.In situ hybridization for Th, Chrna6 and Chrnb3 on sagittal sections of Pitx3+/+ and Pitx3−/− mice. Expression of the cholinergic receptor subunits Chrna6 and Chrnb3 depends on Pitx3.In situ hybridization for Th, Chrna6 and Chrnb3 on sagittal sections of Pitx3+/+ and Pitx3−/− mice. The expression of Chrna6 is prominently downregulated in a medial subset of mdDA neurons as a consequence of Pitx3 ablation, whereas the transcript of Chrnb3 could not be detected in any mdDA neurons in Pitx3−/− mice. L, lateral; M, medial. Koushik Chakrabarty et al. Biology Open 2012;1:693-704 © 2012. Published by The Company of Biologists Ltd