SYCE2 induces resistance to ionizing radiation and cisplatin in somatic cells. SYCE2 induces resistance to ionizing radiation and cisplatin in somatic.

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SYCE2 induces resistance to ionizing radiation and cisplatin in somatic cells. SYCE2 induces resistance to ionizing radiation and cisplatin in somatic cells. (A, B) Colony survival of MCF7 cells transfected with nontargeting control siRNA and SYCE2-targeting siRNA after 4-Gy x-ray irradiation (A) and treatment with 50 μM cisplatin (B). (C, D) Sensitivities of the mock cells and FLAG-SYCE2–expressing RPE cells after treatment with ionizing radiation (C) and cisplatin (D). Noriko Hosoya et al. LSA 2018;1:e201800021 © 2018 Hosoya et al.