Patterns of care in hilar node-positive (N1) non–small cell lung cancer: A missed treatment opportunity? Matthew J. Bott, MD, Aalok P. Patel, BS, Vivek.

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Presentation transcript:

Patterns of care in hilar node-positive (N1) non–small cell lung cancer: A missed treatment opportunity? Matthew J. Bott, MD, Aalok P. Patel, BS, Vivek Verma, MD, Traves D. Crabtree, MD, Daniel Morgensztern, MD, Clifford G. Robinson, MD, Graham A. Colditz, PhD, Saiama Waqar, MD, Daniel Kreisel, MD, PhD, A. Sasha Krupnick, MD, G. Alexander Patterson, MD, Stephen Broderick, MD, Bryan F. Meyers, MD, Varun Puri, MD, MSCI The Journal of Thoracic and Cardiovascular Surgery Volume 151, Issue 6, Pages 1549-1558.e2 (June 2016) DOI: 10.1016/j.jtcvs.2016.01.058 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Kaplan-Meier curves for OS in patients with clinical N1-positive NSCLC receiving (A) adequate treatment versus inadequate or no treatment and (B) inadequate treatment versus no treatment (P < .001 for both). Cum, Cumulative; Dx, diagnosis. (See Tables E1 and E2 for 95% confidence intervals and number at risk periodically with time.) The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1549-1558.e2DOI: (10.1016/j.jtcvs.2016.01.058) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Kaplan-Meier curve for OS in patients with clinical N1-positive NSCLC undergoing definitive CRT versus those undergoing surgical resection (P < .001). Cum, Cumulative; Dx, diagnosis; CRT, chemoradiation. (See Table E3 for 95% confidence intervals and number at risk periodically with time.) The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1549-1558.e2DOI: (10.1016/j.jtcvs.2016.01.058) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Kaplan-Meier curve for OS in 2308 propensity score–matched patient pairs undergoing either surgical resection or definitive CRT for the treatment of N1 node-positive NSCLC (P < .001). Cum, Cumulative; Dx, diagnosis; CRT, chemoradiation. (See Table E4 for 95% confidence intervals and number at risk periodically with time.) The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1549-1558.e2DOI: (10.1016/j.jtcvs.2016.01.058) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Propensity-matched survival for patients undergoing surgery versus CRT for N1-positive NSCLC. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1549-1558.e2DOI: (10.1016/j.jtcvs.2016.01.058) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions