Allogeneic Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for Treatment of Marrow Failure Disorders  Lauri M. Burroughs, Akiko.

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Allogeneic Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for Treatment of Marrow Failure Disorders  Lauri M. Burroughs, Akiko Shimamura, Julie-An Talano, Jennifer A. Domm, Kelsey K. Baker, Colleen Delaney, Haydar Frangoul, David A. Margolis, K. Scott Baker, Eneida R. Nemecek, Amy E. Geddis, Brenda M. Sandmaier, H. Joachim Deeg, Rainer Storb, Ann E. Woolfrey  Biology of Blood and Marrow Transplantation  Volume 23, Issue 10, Pages 1669-1677 (October 2017) DOI: 10.1016/j.bbmt.2017.06.002 Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 CD3+ and CD33+ donor chimerism in 14 patients conditioned with treosulfan-based conditioning. Shown are the percent donor chimerism of sorted peripheral blood CD3+ (A) and CD33+ (B) subsets according to day after transplant. Overlapping points at days +28, +80, +180, years, and at 100% chimerism, are jittered slightly to improve visibility. Biology of Blood and Marrow Transplantation 2017 23, 1669-1677DOI: (10.1016/j.bbmt.2017.06.002) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Disease-free survival. Shown is the Kaplan-Meier estimate of disease-free survival for 14 patients with bone marrow failure disorders who received treosulfan-based conditioning. Biology of Blood and Marrow Transplantation 2017 23, 1669-1677DOI: (10.1016/j.bbmt.2017.06.002) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions