The discovery and characterization of the leukotrienes

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Presentation transcript:

The discovery and characterization of the leukotrienes Charles N. Serhan, PhD  Journal of Allergy and Clinical Immunology  Volume 118, Issue 4, Pages 972-976 (October 2006) DOI: 10.1016/j.jaci.2006.08.018 Copyright © 2006 Terms and Conditions

Fig 1 Bengt Samuelsson around the time of the discovery of the leukotrienes in his office at Kemi II, Karolinska Institute, Stockholm, along with the 5-lipoxygenase pathway and its role in the biosynthesis of leukotrienes as it was presented at the time of its elucidation and the 1982 Nobel Prize. Today, many components of this important system are known, including the enzymes, proteins, and genes governing their expression. Journal of Allergy and Clinical Immunology 2006 118, 972-976DOI: (10.1016/j.jaci.2006.08.018) Copyright © 2006 Terms and Conditions

Fig 2 Samuelsson (left) receiving the 1982 Nobel Prize and shaking hands with the King of Sweden (right). Photograph used with permission from Scanpix. Journal of Allergy and Clinical Immunology 2006 118, 972-976DOI: (10.1016/j.jaci.2006.08.018) Copyright © 2006 Terms and Conditions