Christopher E. Gates, MDa (by invitation), Carolyn E

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Presentation transcript:

Prevalence of p53 mutations in patients with squamous cell carcinoma of the esophagus Christopher E. Gates, MDa (by invitation), Carolyn E. Reed, MDa (by invitation), Jonathan S. Bromberg, MD, PhDa,b (by invitation), Eric T. Everett, PhDc (by invitation), Paul L. Baron, MDa (by invitation) The Journal of Thoracic and Cardiovascular Surgery Volume 108, Issue 1, Pages 148-152 (July 1994) DOI: 10.5555/uri:pii:S0022522394702314 Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 1 A representative point mutation: Sample EH, anti-sense strand, beginning with codon 280 reads: CTC TCT GAC. The accepted sequence is CTC TCT GGC. This G to A transition at codon 282 in the anti-sense strand corresponds to a C to T transition in the sense strand, which results in an arginine to cysteine missense mutation in the p53 protein. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 148-152DOI: (10.5555/uri:pii:S0022522394702314) Copyright © 1994 Mosby, Inc. Terms and Conditions