Volume 86, Issue 5, Pages (November 2014)

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Volume 86, Issue 5, Pages 1023-1030 (November 2014) Pneumococcal pneumonia infection is associated with end-stage renal disease in adult hospitalized patients Shih-Ting Huang, Cheng-Li Lin, Yen-Jung Chang, Yuh-Pyng Sher, Ming-Ju Wu, Kuo-Hsiung Shu, Fung-Chang Sung, Chia-Hung Kao Kidney International Volume 86, Issue 5, Pages 1023-1030 (November 2014) DOI: 10.1038/ki.2014.79 Copyright © 2014 International Society of Nephrology Terms and Conditions

Figure 1 Patient selection flowchart. Kidney International 2014 86, 1023-1030DOI: (10.1038/ki.2014.79) Copyright © 2014 International Society of Nephrology Terms and Conditions

Figure 2 Cumulative incidence of end-stage renal disease curves in patients with and without pneumococcal pneumonia after accounting for death and withdrawal from the national health insurance system as competing risks. Kidney International 2014 86, 1023-1030DOI: (10.1038/ki.2014.79) Copyright © 2014 International Society of Nephrology Terms and Conditions

Figure 3 Summaries of hypothetical mechanisms of renal injury following pneumococcal pneumonia. CrP, C-reactive protein; FSGS, focal segmental glomerulosclerosis; HUS, hemolytic uremia syndrome; ICAM-1, intercellular adhesion molecule-1; IL-1, interleukin-1; IL-6, interleukin-6; NSAIDs, nonsteroidal anti-inflammatory drugs; PIGN, postinfectious glomerulonephritis; suPAR, soluble urokinase-type plasminogen activator receptor; TMA, thrombotic microangiopathy; TNF-α, tumor necrosis factor-α; TGF-β, transforming growth factor-β. Kidney International 2014 86, 1023-1030DOI: (10.1038/ki.2014.79) Copyright © 2014 International Society of Nephrology Terms and Conditions