Waddington’s Valleys and Captain Cook’s Islands

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Presentation transcript:

Waddington’s Valleys and Captain Cook’s Islands Michael H. Sieweke Cell Stem Cell Volume 16, Issue 1, Pages 7-8 (January 2015) DOI: 10.1016/j.stem.2014.12.009 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Waddington’s and Cook’s Reprogramming Landscapes Alternative models of Waddington’s (A) and Cook’s (B) reprogramming landscapes showing mature cell types (a, b, and c) and intermediate states (1, 2, 3) of cellular development. Lines in (B) retrace a hypothetical Polynesian settlement of French Polynesia from west to east (red) and Captain Cook’s route from east to west (blue) as models of development and reprograming, respectively. Cell Stem Cell 2015 16, 7-8DOI: (10.1016/j.stem.2014.12.009) Copyright © 2015 Elsevier Inc. Terms and Conditions