Volume 134, Issue 7, Pages (June 2008)

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Presentation transcript:

Volume 134, Issue 7, Pages 1917-1926 (June 2008) Hepatic Involvement and Portal Hypertension Predict Mortality in Chronic Granulomatous Disease Jordan J. Feld, Nadeem Hussain, Elizabeth C. Wright, David E. Kleiner, Jay H. Hoofnagle, Sushil Ahlawat, Victoria Anderson, Dianne Hilligoss, John I. Gallin, T. Jake Liang, Harry L. Malech, Steven M. Holland, Theo Heller Gastroenterology Volume 134, Issue 7, Pages 1917-1926 (June 2008) DOI: 10.1053/j.gastro.2008.02.081 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 Platelet slopes from representative patients who (A) died and (B) survived to the end of the follow-up period. Gastroenterology 2008 134, 1917-1926DOI: (10.1053/j.gastro.2008.02.081) Copyright © 2008 AGA Institute Terms and Conditions

Figure 2 Estimate of the survival function for each of the determinants of mortality based on the Cox proportional hazards model. The curves compare the survival estimates for patients with and without (A) declining platelet slope (B) ALP increases, and (C) a history of liver abscess. Each curve is adjusted for all factors in the multivariable Cox model. (D) This figure compares the survival function for patients with all 3 determinants of mortality with that for patients with none of these factors. Gastroenterology 2008 134, 1917-1926DOI: (10.1053/j.gastro.2008.02.081) Copyright © 2008 AGA Institute Terms and Conditions