Effects of Z-FA-FMK on SMN protein expression in type II SMA patient fibroblast cells (GM22592). Effects of Z-FA-FMK on SMN protein expression in type.

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Effects of Z-FA-FMK on SMN protein expression in type II SMA patient fibroblast cells (GM22592). Effects of Z-FA-FMK on SMN protein expression in type II SMA patient fibroblast cells (GM22592). (A, B) In SMA type II fibroblast cells, vehicle (DMSO) or Z-FA-FMK were applied for 2 d; Western blot analysis revealed a dose-dependent increase in the expression of SMN proteins after treatment with Z-FA-FMK. n = 4. (C) qRT-PCR showing the mRNA expression in fibroblast cells after treatment with different concentrations of Z-FA-FMK. Data were presented as mean ± SEM, n = 3. *P < 0.05, as compared with the DMSO-treated group by two-tailed t test. Yiran Wang et al. LSA 2019;2:e201800268 © 2019 Wang et al.