Image examples of the improved detection of mixed white matter-gray matter lesions on the DIR pulse sequence. Image examples of the improved detection.

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High-signal-intensity lesions on T2-weighted MR images

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Presentation transcript:

Image examples of the improved detection of mixed white matter-gray matter lesions on the DIR pulse sequence. Image examples of the improved detection of mixed white matter-gray matter lesions on the DIR pulse sequence. These images were obtained from a 40-year-old woman with a relapsing-remitting course of MS (disease duration, 165 months; EDSS, 6) presenting with a high lesion load on the MR imaging, including mixed white matter-gray matter lesions. Top row, an example of different classifications of a lesion using different pulse sequences. A lesion (arrow) was prospectively classified as a juxtacortical lesion on the T2 TSE and FLAIR images. Because of the better delineation of the white and gray matter on the DIR image, this lesion had to reclassified into a mixed white matter-gray matter lesion. Bottom row, an example of the higher conspicuity of a cortical lesion (arrow) on the DIR image that was not prospectively identified on the corresponding T2 TSE and FLAIR images. Another lesion (open arrow) could be easily identified and categorized on the DIR image as a pure juxtacortical lesion without touching the cortex. M.P. Wattjes et al. AJNR Am J Neuroradiol 2007;28:54-59 ©2007 by American Society of Neuroradiology