Interleukin-1 blockade effects interferon (IFN)-γ production by multiple cell types. a) Gating strategy for flow cytometry: CD56+ natural killer (NK) cells.

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Fig. 2. Comparison of the Th1/Th2 ratio and the percentages of Th1 and Th2 cells between normal and allergic individuals. (A) The Th1/Th2 ratio observed.
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Interleukin-1 blockade effects interferon (IFN)-γ production by multiple cell types. a) Gating strategy for flow cytometry: CD56+ natural killer (NK) cells (CD3−CD56+), CD3+ T-cells (CD3+CD56−) and other cells (CD3−CD56−) were identified within the total ga... Interleukin-1 blockade effects interferon (IFN)-γ production by multiple cell types. a) Gating strategy for flow cytometry: CD56+ natural killer (NK) cells (CD3−CD56+), CD3+ T-cells (CD3+CD56−) and other cells (CD3−CD56−) were identified within the total gated lymphocytes. The percentage of IFN-γ-producing cells was then evaluated in each of the cell subtypes. b) Percentage of non-typeable Haemophilus influenzae (NTHi)-stimulated IFN-γ-producing cells in the absence and presence of interleukin-1 receptor antagonist (IL-1Ra) at 24 h post-stimulation (n=9). *: p<0.05 by Wilcoxon matched-pairs signed rank test; **: p<0.01 by Wilcoxon matched-pairs signed rank test. Alice C-H. Chen et al. ERJ Open Res 2017;3:00025-2017 ©2017 by European Respiratory Society

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