Chapter 11 Amines Adel M. Awadallah Islamic University of Gaza Organic chemistry for medicine and biology students Chem 2311 Chapter 11 Amines By Prof. Dr. Adel M. Awadallah Islamic University of Gaza

Physical Properties of Amines

The carbon-nitrogen triple bond is reduced using hydrides to give a primary amine. For example, with ethanenitrile you get ethylamine The reduction of nitriles using hydrogen and a metal catalyst

The more ammonia there is in the mixture, the more the forward reaction is favoured..

Amines as Bases

Aliphatic amines are stronger bases than aromatic amines because of the resonance in aromatic amines

Electron-donating groups increase the basicity of amines, and electron-withdrawing groups decrease their basicity , and amines are stronger bases than amides