Genome Scan of Human Systemic Lupus Erythematosus by Regression Modeling: Evidence of Linkage and Epistasis at 4p16-15.2 C. Gray-McGuire, K.L. Moser,

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Genome Scan of Human Systemic Lupus Erythematosus by Regression Modeling: Evidence of Linkage and Epistasis at 4p16-15.2 C. Gray-McGuire, K.L. Moser, P.M. Gaffney, J. Kelly, H. Yu, J.M. Olson, C.M. Jedrey, K.B. Jacobs, R.P. Kimberly, B.R. Neas, S.S. Rich, T.W. Behrens, J.B. Harley The American Journal of Human Genetics Volume 67, Issue 6, Pages 1460-1469 (December 2000) DOI: 10.1086/316891 Copyright © 2000 The American Society of Human Genetics Terms and Conditions

Figure 1 Chromosomes containing regions with SIBPAL2 significance <.01. Centimorgans are plotted on the X-axis and P values on the Y-axis. Asterisks(*) indicate locations of other linkage signals identified on chromosomes 4 and 6 (Gaffney et al. 1998; Lindqvist et al. 2000). The American Journal of Human Genetics 2000 67, 1460-1469DOI: (10.1086/316891) Copyright © 2000 The American Society of Human Genetics Terms and Conditions

Figure 2 Chromosomes containing regions with ARP LOD scores >2.0. Centimorgans are plotted on the X-axis and LOD scores on the Y-axis. Asterisks (*) indicate locations of other linkage signals identified on chromosomes 4 and 6 (Gaffney et al. 1998; Lindqvist et al. 2000). The American Journal of Human Genetics 2000 67, 1460-1469DOI: (10.1086/316891) Copyright © 2000 The American Society of Human Genetics Terms and Conditions