The alignment of P-type ATPase-like domains of TgATPaseP-GC, PfGCα, and PfGCβ with the members of human P4-ATPases. The alignment of P-type ATPase-like.

Slides:

Advertisements

Similar presentations

Bioinformatics Analysis of YqjG: an introduction and some questions YqjG: “Uncharacterized protein” from Escherichia coli UniProt ID = P42620 (YQJG_ECOLI)

Advertisements

AMPK and Apoptosis Emeline Van Goethem José Manuel López Apoptosis or programmed cell death is an important part of the development of all multicellular.

Cystic Fibrosis and Gastric Acid Transport March 11, 2008 CH353 Group Project Sidani et al. 2007, DeltaF508 mutation results in impaired gastric acid secretion,

From: Phylogenetic Analysis of the ING Family of PHD Finger Proteins

Supplementary Figure 1 ORF2 ORF3 Nelorpivirus (Group I Negevirus)

C N TM1 (a) WARLVMCFVLVLITTSIWTLIMV SOSUI PSORT II

0.005 E. billingiae Eb661 E. amylovora ACW5400

Supplemental Figure S2. Sequence comparison of the Arabidopsis homologue of PAHX with human PHYD1 (phytanoyl-CoA dioxygenase domain containing 1) and human.

Fig. 1. NS1 protein alignment and linear epitope mapping of the 10 antibodies used to run the DENV serotype–specific NS1 rapid tests, pan-DENV NS1 test,

Sequence alignment of C-terminal phosphorylated plant aquaporins

Sequence and comparison of the SDS protein.

Supplemental Figure S1. Alignment of drimenol synthase amino acid sequences from P. hydropiper and V. officinalis. Amino acid sequences were aligned with.

Multiple sequence alignment and analysis of SOFL proteins.

Sebastian Meyer, Raimund Dutzler Structure

Phosphopeptides identified harboring minimal binding motifs

Model of human CLC-Kb transporter topology and positions of amino acid exchanges due to mutations in the CLCNKB gene as identified in Bartter syndrome.

MOSPD2 is a putative tail‐anchored protein

Alignment of H-NS, H-NS2, and StpA amino acid sequences.

(A) Six missense mutations in six essential genes that are not in annotated functional domains. (A) Six missense mutations in six essential genes that.

Alignment time for Clustal Omega (red), MAFFT (blue), MUSCLE (green) and Kalign (purple) against the number of sequences of HomFam test sets. Alignment.

STAT Genes Found in C. elegans

Volume 20, Issue 6, Pages (December 2005)

Fine mapping assay with a G6 peptide library identifies two epitopes recognized by the anti-P39 antibody. Fine mapping assay with a G6 peptide library.

Volume 22, Issue 10, Pages (October 2014)

Sequence alignment of PHCCEx domains with secondary structure elements of the Tiam2 PHCCEx domain at the top. Sequence alignment of PHCCEx domains with.

Firefly luciferase: the structure is known, but the mystery remains

Schematic diagram of the proposed structure of CFTR

Volume 23, Issue 3, Pages (August 2006)

Fig. 1 A single amino acid difference in the ATP-binding domain of GSK3α and GSK3β results in structural and topological differences. A single amino acid.

Volume 6, Issue 6, Pages (December 2000)

Alex Bateman, Cyrus Chothia Current Biology

Amino acid sequence alignment of beetle luciferases.

Bioinformatics analysis of the small TbTim amino acid sequences.

Copper Transporters: CTR1, CTR2, ATP7A, & ATP7B

Figure 1 Dissimilar mutation distributions in 88% identical ATP1A2 and ATP1A3 proteins Dissimilar mutation distributions in 88% identical ATP1A2 and ATP1A3.

Identification of the GCS1 ortholog in Gonium pectorale.

Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets by Weidong Jing, Mehmet Yabas, Angelika Bröer, Lucy Coupland, Elizabeth E. Gardiner,

AKAP15 coimmunoprecipitates with CaV1

Alignment of putative chicken HB-EGF to mammalian HB-EGF proteins and the domains of HB-EGF. Alignment of putative chicken HB-EGF to mammalian HB-EGF proteins.

Sequence conservation across the Ub-binding sites of human USPs

Figure 1 Pedigree and genetic findings

Multiple sequence alignment of STAT6 and other STAT proteins produced by ClusterW and ESpript (espript.ibcp.fr/ESPript/ESPript/). Multiple sequence alignment.

The saturation scan database for Ubv.2.1 (A) and Ubv.21.4 (B).

Figure 3 Similar but restricted distributions of pathogenic variants in the P domain Similar but restricted distributions of pathogenic variants in the.

PfSec13 is a structural homolog of ScSec13·Nup145C.

(A) Deduced amino acid sequence of the D2SV cDNA cloned from the mouse heart RNA. The novel 20 amino acid C-terminus (CT) is underlined. (A) Deduced amino.

Annoted amino acid sequence of Aedes aegypti gliotactin (Gli).

Fig. 4. The predicted protein domains in sma

Schematic representation of the domain structures of insect enzymes involved in chitin metabolism. Schematic representation of the domain structures of.

Alignment of the fast/developmental and IIM MYH genes.

Alignment of Stau dsRBDs.

Mosquito GluCl alignment and anti-AgGluCl IgG specificity.

Isoforms and domain structures of mammalian and invertebrate spectraplakins. Isoforms and domain structures of mammalian and invertebrate spectraplakins.

The sequence alignment of GC1 and GC2 domains from TgATPaseP-GC with other representative cyclases identifies signature residues. The sequence alignment.

Alignment of the deduced amino acid sequences of the myosin light chain 2 (MLC2) proteins. Alignment of the deduced amino acid sequences of the myosin.

Reconstituted Xenopus Lnp forms stacked membrane discs.

Amino acid sequence alignment of Calliphora (Cv) and Drosophila (Dm) rhodopsins. Amino acid sequence alignment of Calliphora (Cv) and Drosophila (Dm) rhodopsins.

Phosphopeptides identified harboring minimal binding motifs

Comparison of the sequences of Fzo/Mfn and structure of mammalian Mfn2

Phylogenetic analysis reveals a protozoan-specific clading of TgATPaseP-GC. Phylogenetic analysis reveals a protozoan-specific clading of TgATPaseP-GC.

Alignment of the deduced amino acid sequence of rat olfactory CNCβ1b with bovine rod CNCβ1a. Alignment of the deduced amino acid sequence of rat olfactory.

Structural features of Rps26a.

Cecilia P. Sanchez, Paul Horrocks, Michael Lanzer Cell

Sequence comparisons of fungal HOG1 orthologues.

Mutations in the Human Orthologue of the Mouse underwhite Gene (uw) Underlie a New Form of Oculocutaneous Albinism, OCA4 J.M. Newton, Orit Cohen-Barak,

Conserved motifs in the ABC

IF2 and structural homologues.

Sequence alignment of colicin lysis proteins.

TRPC5 ion conduction pathway compared with TRPC4 and other TRPCs

Alignment of the Amino Acid Sequences of NCS and Other PR10/Bet v1 Proteins from Various Plant Species.Deduced amino acid sequences were aligned using.

Presentation transcript:

The alignment of P-type ATPase-like domains of TgATPaseP-GC, PfGCα, and PfGCβ with the members of human P4-ATPases. The alignment of P-type ATPase-like domains of TgATPaseP-GC, PfGCα, and PfGCβ with the members of human P4-ATPases. The human P4-ATPases were aligned by MAFFT alignment server (v7) (Katoh & Standley, 2013), and then merged with the aligned ATPase domains of TgATPaseP-GC, PfGCα, and PfGCβ using MAFFT merge. The alignment was trimmed, as indicated by horizontal lines, and signature residues were color-coded with the Clustal Omega program (>30% sequence conservation). Selected amino acids that are essential for ATP binding and phosphorylation, and transmembrane helices are boxed in black. Transmembrane topology of ATP8A1 retrieved from TMHMM Server (v2) (Sonnhammer et al, 1998) was used as a reference. Organism abbreviations and accession numbers: P-type ATPase-like domain of TgATPaseP-GC, T. gondii (EPR59074.1); PfGCα, P. falciparum (AJ245435.1); PfGCβ, P. falciparum (AJ249165.1); and P4-ATPases of Homo sapiens: ATP8A1 (Q9Y2Q0.1), ATP8B4 (Q8TF62.3), ATP9A (O75110.3), ATP10A (O60312.2), and ATP11C (Q8NB49.3). Özlem Günay-Esiyok et al. LSA 2019;2:e201900402 © 2019 Günay-Esiyok et al.