Representative histological sections of porcine lungs obtained after transbronchial cryoablation. Representative histological sections of porcine lungs.

Slides:



Advertisements
Similar presentations
The significantly different metabolites between the systemic inflammatory response syndrome SIRS (n=15) and sepsis (n=35) groups (A); the sepsis (n=10)
Advertisements

Patients with exacerbations of chronic obstructive pulmonary disease admitted to hospital according to the day of the week (A), and presenting to the emergency.
Successful tissue collection in patients with relapse of EGFR-positive adenocarcinoma after EGFR-TKI treatment. Successful tissue collection in patients.
The top 25 analytes by relevant q-value differentially expressed in HIV with COPD. The top number is m/z and the bottom number is RT. Y-axis is intensity.
For most patients with asthma airway response becomes flatter after 1000 µg of inhaled corticosteroid, but systemic activity (measured by serum cortisol.
Variable life adjusted display (VLAD chart) showing observed versus expected mortability with cumulative lives lost below the x-axis and cumulative lives.
Association of sputum colour score with (A) total cell counts; (B) neutrophil proportion; (C) neutrophil number and (D) CXCL-8 concentration. Association.
Serum levels of angiopoietin-like protein 4 (ANGPTL4) according to patients with chronic obstructive pulmonary disease and controls without any lung disease.
(A) Refined profile principal component analysis loading weights plot was used to derive insight into possible association of biomarkers. (A) Refined profile.
Percentage of patients per stage of oesophageal cancers in the two trials, overall difference P
Sample figures of typical bronchoscopy findings illustrating the effect of i-scan image enhancement technique and differences in vascular patterns. Sample.
Comparison of the age-associated prevalence (y axis) in the Catalan Healthcare Surveillance System (CHSS) and Medicare datasets of selected disease groups.
Bland-Altman plots comparing intraobserver PWV repeatability.
(A) A pie chart demonstrating the size ranges of aspirated SCLN (total n=228). (A) A pie chart demonstrating the size ranges of aspirated SCLN (total n=228).
A temperature inversion causing cold air drainage to accumulate as fog in the low-lying areas of the Tamar Valley and Midlands (Source: National Aeronautics.
Distributions of ratios of MFI by visit for the stimulated/unstimulated, stimulated/inhibited+stimulated and inhibited+stimulated/unstimulated samples.
Prevalence (x axis) of disease groups (DGs) (y axis) in the population of Medicare (light cyan) and Catalan Healthcare Surveillance System (CHSS) (light.
British thoracic Society/Scottish Intercollegiate Guidelines Network (BTS/SIGN) 2014 version of guidelines on the management of asthma: summary of stepwise.
Patients’ pathways to Accident and Emergency (A&E)
Multirater agreement (Fleiss' κ) between 6 paediatricians and 6 doctors for adults on the presence of crackles and wheezes (inspiratory or expiratory)
A) The flexible 1.9 mm diameter and 900 mm length cryoprobe, b) connected to the cryotherapy equipment. c) Marks on the distal area of the probe (1 cm.
Incidence of choking in London, UK, by gender per 1000 population by age group. Incidence of choking in London, UK, by gender per 1000 population by age.
Peripheral blood eosinophil levels based on a threshold of (A) 150 cells/μL, patients not randomised to inhaled corticosteroids (ICS)-containing treatment.
Use of medication among chronic obstructive pulmonary disease (COPD) cases by age and place of residence among 1586 COPD cases. The dark grey bar represents.
Differences in gut bacterial microbiota composition are associated with (A) degree of aeroallergen sensitisation; (B) lung function as measured by FEV1.
Change from baseline in the severity of morning cough and severity of difficulty bringing up phlegm in the morning over the study period in the active-comparator.
Prevalence of chronic obstructive pulmonary disease (COPD) defined by different criteria by age, and place of residence. The dark grey bar represents ‘rural’
Diagrammatic representation of diagnostic performance characteristics of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in.
Forest plots for randomised and cluster randomised controlled trials from Cochrane review Biomarkers as point-of-care tests to guide prescription of antibiotics.
Comparison of the serum levels of the three vascular endothelial growth factor (VEGF) types in healthy volunteers and patients with idiopathic pulmonary.
Kaplan–Meier curves for the time until myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA)-positive conversion (A: MPO-ANCA, B: proteinase 3.
Comparison of the effects of intercostal tube drainage of pleural fluid (drain group: solid bars) and no intervention (control group: open bars) on oxygenation.
Receiver under the operator characteristic (ROC) curve for the test accuracy of the final risk score in the entire external validation sample (c statistic=0.84,
Changes in median exhaled CO levels from baseline to 12 weeks in quitters (n=183) and continuous smokers (n=94). Changes in median exhaled CO levels from.
Changes in St. George's Respiratory Questionnaire (SGRQ) scores from baseline to 12 weeks for total samples (n=277), quitters (n=183) and continuous smokers.
Trial design. Study design schematic of the PF-ILD trial followed by a separate open-label trial (optional): part A (visits 1 through 9 over 52 weeks)
Slope of FEV1 by age at enzyme replacement therapy (ERT) initiation FEV1 z-score slope (y-axis) by age categorised in three groups (red, ERT initiation 
Comparative receiver operating characteristic (ROC) curves and the area under the curve (AUC) in association with 30-day mortality for severity scores.
Weight and cardiopulmonary parameter changes in C57Bl/6 mice post IT-LPS or PBS. Weight changes were assessed in C57Bl/6 instilled via IT route with 50 µg.
OBP-401 precisely labels orthotopic lung cancer.
Transit time technique: (A) axial HASTE through the pulmonary trunk bifurcation; (B) short axis RPA; (C) short axis MPA; (D) short axis LPA; (E) flow curves.
Receiver operating characteristic curves (ROC) for the metabolites between the systemic inflammatory response syndrome (n=15) and sepsis (n=35) groups.
Immunohistochemical characterisation of CCL21 expression.
Worse eDiary scores are associated the more rescue inhaler usage and reduced step counts over both an individual day and 3-week summary period. Worse eDiary.
(A) ERK spectra peak identification using three different primary antibodies (ERK1/2, ERK1 and phospho-ERK1/2) in one sample (emphysema) allowing accurate.
Plot of change in incremental shuttle walk test following pulmonary rehabilitation according to ACE (insertion/deletion) polymorphism. Plot of change in.
Manhattan plot for the association between COPD and DNA methylation in never smokers (left) and current smokers (right). Manhattan plot for the association.
Changes in 6 min walk distance (6MWD) for combined pulmonary fibrosis and emphysema (CPFE) (n=15), and chronic obstructive pulmonary disease (COPD) (n=37).
Prevalence of air flow obstruction (age-adjusted) by (A) lower limit of normal of forced expiratory ratio versus self-reported doctor diagnosis and (B)
(A and B) Representative peaks using AKT primary antibody in normal lung and emphysema and tumour and matched normal lung, respectively. (A and B) Representative.
Illustrated positional relationship of the cryoprobe and thermocouples, and typical chronological temperature changes of targeted lung tissue areas according.
All microorganism strains isolated from the sputum during the study period. All microorganism strains isolated from the sputum during the study period.
Receiver operating characteristic ROC curve of Lung Clearance Index (LCI)1/40, LCI1/30, LCI1/20, LCI1/10 and inverse forced expiratory volume in 1 s %
Screening test accuracy of the final risk score at a threshold of ≥2
PET of whole body distribution in coronal section at 1 and 5 hours after labelled multipotent adultprogenitorcells (MAPCs) delivery intravenous or endobronchial.
Spider diagram showing choking incident count by day of week and hour of day. Spider diagram showing choking incident count by day of week and hour of.
HFNC off is compared with HFNC 30 L/min and HFNC 50 L/min for tidal volume. HFNC off is compared with HFNC 30 L/min and HFNC 50 L/min for tidal volume.
(A) Contamination of individual nebuliser components and contamination rates and organism types in patients with multiple nebulisers; five patients in.
Weekly bronchitis cases (circles, left hand axis) and particulate matter with a diameter below 10 µ (PM10) (crosses, right hand axis), with smoothed curves.
(A) Posterioranterior (PA) chest X-ray demonstrates pneumomediastinum in the anterior and middle mediastinum extending into the cervical soft tissues.
COPD Action Plan adherence.
UK Singing for Lung Health groups: the blue points on the map represent groups run by a BLF trained leader. UK Singing for Lung Health groups: the blue.
Vitamin D3 increased ASL antimicrobial activity in non-smokers.
Prevalence of chronic obstructive pulmonary disease (COPD) defined by different criteria by region. The dark grey bar represents ‘symptom-based COPD’,
Comparison of the serum and bronchoalveolar lavage fluid (BALF) levels of CCL21 among healthy volunteers and patients with idiopathic pulmonary fibrosis.
Chest CT scans obtained at the time of first onset of illness (A), at the time of the first visit to our hospital (B), on the day of bronchoscopic examination.
An illustration of experimental transbronchial cryoablation with a rigid cryoprobe (A) and photographs of transbronchial introduction of a cryoprobe (B)
Stacked bar charts for key predictor variables (representativeness of SLS COPD). Stacked bar charts for key predictor variables (representativeness of.
Frequency distribution histograms of the Exacerbations of Chronic Pulmonary Disease Tool (EXACT) total, the COPD Assessment Test (CAT), the St George’s.
Receiver operating characteristic (ROC) curves for Saint George’s Respiratory Questionnaire (SGRQ) category scores predicting chronic obstructive pulmonary.
Presentation transcript:

Representative histological sections of porcine lungs obtained after transbronchial cryoablation. Representative histological sections of porcine lungs obtained after transbronchial cryoablation. A composite histological photograph shows a transverse section through the axis of a bronchus in which a cryoprobe was inserted (A) (bar=2 mm). High power fields show alveoli and pleura in the destruction zone (B) and the bronchus and an accompanying pulmonary artery (C) after transbronchial cryoablation (bar=100 µm). Composite histological Photographs of porcine lung sections including the major axis of a cryoprobe tract after transbronchial cryoablation showing a reddish destruction zone along a bronchus (D) (bar=2 mm). Mitsutomo Kohno et al. BMJ Open Resp Res 2018;5:e000315 ©2018 by British Thoracic Society