Acute Renal Failure due to IgM-λ Glomerular Thrombi and MPGN-Like Lesions in a Patient With Angioimmunoblastic T-Cell Lymphoma Naoto Miura, MD, Keisuke Suzuki, MD, Masabumi Yoshino, MD, Wataru Kitagawa, MD, Harutaka Yamada, MD, Hiroshi Ohtani, MD, Kensuke Joh, MD, Hirokazu Imai, MD, FJSIM American Journal of Kidney Diseases Volume 48, Issue 1, Pages e3-e9 (July 2006) DOI: 10.1053/j.ajkd.2006.03.084 Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions
Fig 1 Light microscopy of a renal biopsy specimen shows (A) mild mesangial cell proliferation with lobular formation and thrombi in the glomerular capillary lumen and (B) foam cell infiltration and double contour, as well as glomerular thrombi. ([A] Azan stain, [B] periodic acid–methenamine silver stain; [A, B] original magnification ×400.) American Journal of Kidney Diseases 2006 48, e3-e9DOI: (10.1053/j.ajkd.2006.03.084) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions
Fig 2 Immunofluorescence microscopy shows weakly positive IgG and IgA, negative C3, and strongly positive IgM and λ. American Journal of Kidney Diseases 2006 48, e3-e9DOI: (10.1053/j.ajkd.2006.03.084) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions
Fig 3 Electron microscopy of a renal biopsy specimen shows electron-dense deposits in the subendothelial space and foam cell infiltration in the mesangial area, but no fibrillar structure. (Lower left, original magnification ×2,800; upper right, original magnification ×8,000.) American Journal of Kidney Diseases 2006 48, e3-e9DOI: (10.1053/j.ajkd.2006.03.084) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions
Fig 4 Electron microscopy shows glomerular thrombi and foam cell infiltration in the mesangial area, but no specific structure. (Lower left, original magnification ×1,500; upper right, original magnification ×6,500.) American Journal of Kidney Diseases 2006 48, e3-e9DOI: (10.1053/j.ajkd.2006.03.084) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions