Eung-Ji Lee, M. Sc. , Bermseok Oh, Ph. D. , Jong-Young Lee, Ph. D

Slides:

Advertisements

Similar presentations

Clinically significant and sustained weight loss is achievable in obese women with polycystic ovary syndrome followed in a regular medical practice Lysanne.

Advertisements

Elias M. Dahdouh, M. D. , M. Sc. , Jacques Balayla, M. D

Benefit of uterine artery ligation in laparoscopic myomectomy

Association of insulin receptor genetic variants with polycystic ovary syndrome in a population of women from Central Europe Felicia A. Hanzu, M.D.,

Akanksha Mehta, M.D., Mark Sigman, M.D. Fertility and Sterility

Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women Babak Mokhlesi, M.D.,

Fernando Zegers-Hochschild, M.D. Fertility and Sterility

Bjørn Bay, M. D. , Erik Lykke Mortensen, M. Sc

Kalliopi Kotsa, M. D. , Ph. D. , Maria P. Yavropoulou, M. D

Michael M. Alper, M.D. Fertility and Sterility

Michal Youngster, M. D. , Valerie L. Ward, M. D. , M. P. H. , Emily A

Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) in IVF patients with polycystic ovary syndrome: correlations with outcome

Single-gene testing combined with single nucleotide polymorphism microarray preimplantation genetic diagnosis for aneuploidy: a novel approach in optimizing.

Ovarian pregnancy after in vitro fertilization

Association of the −243 A→G polymorphism of the glutamate decarboxylase 2 gene with obesity in girls with premature pubarche Selma Feldman Witchel, M.D.,

Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study Nicole Hope, M.B., B.S., Hon., Luk.

Insulin resistance in oligomenorrheic infertile women with non-polycystic ovary syndrome Shirei Ohgi, M.D., Koji Nakagawa, M.D., Ph.D., Rieko Kojima,

Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study Angela Kerchner, B.A., Whitney Lester,

Sanghoon Lee, M. D. , Elke Heytens, Ph. D. , Fred Moy, Ph. D

Polycystic ovary syndrome: an ancient disorder?

Evaluation of the immature human oocytes from unstimulated cycles in polycystic ovary syndrome patients using a novel scoring system Shan Liu, M.D.,

Signe Altmäe, M. Sc. , Anneli Stavreus-Evers, Ph. D. , Jonatan R

In vitro fertilization availability and utilization in the United States: a study of demographic, social, and economic factors Ahmad O. Hammoud, M.D.,

Live birth of twins derived from zona-free oocytes

Expression of growth differentiation factor-9 and bone morphogenetic protein-15 in oocytes and cumulus granulosa cells of patients with polycystic ovary.

CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype

Rebecca A. Feldman, M. D. , Kathleen O'Neill, M. D. , Samantha F

How old is too old? Challenges faced by clinicians concerning age cutoffs for patients undergoing in vitro fertilization Robert L. Klitzman, M.D. Fertility.

Predictive factors of health-related quality of life in patients with polycystic ovary syndrome: a structural equation modeling approach Fatemeh Bazarganipour,

Oocyte cryopreservation

Mithra L. Narasimhan, M.B.B.S., Ahmed Khattab, M.D.

Evolutionary determinants of polycystic ovary syndrome: part 1

Letrozole versus combined metformin and clomiphene citrate for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized.

Clinical course of depression symptoms and predictors of enduring depression risk in women with polycystic ovary syndrome: Results of a longitudinal study

A microsatellite polymorphism (tttta)n in the promoter of the CYP11a gene in Chinese women with polycystic ovary syndrome Yong Wang, Ph.D., XiaoKe Wu,

Reply of the Authors Fertility and Sterility

CYP11A1 and CYP17 promoter polymorphisms associate with hyperandrogenemia in polycystic ovary syndrome Madhavi Pusalkar, M.Sc., Pervin Meherji, M.D.,

Single-Nucleotide Polymorphisms and Haplotypes in the VEGF Receptor 3 Gene and the Haplotype GC in the VEGFA Gene Are Associated with Psoriasis in Koreans

Raising threshold for diagnosis of polycystic ovary syndrome excludes population of patients with metabolic risk Molly M. Quinn, M.D., Chia-Ning Kao,

Andrew C. Bjonnes, M.S., Richa Saxena, Ph.D., Corrine K. Welt, M.D.

Management of tubal ectopic pregnancy: methotrexate and salpingostomy are preferred to preserve fertility Stephanie Beall, M.D., Ph.D., Alan H. DeCherney,

Clomiphene citrate at 50: the dawning of assisted reproduction

Akanksha Mehta, M.D., Darius A. Paduch, M.D., Ph.D.

Hélio Sato, M. D. , Ph. D. , Naiara C. Nogueira-de-Souza, M. Sc. , Ph

Increased secretion of amylin in women with polycystic ovary syndrome

Prevalence of polycystic ovary syndrome in adolescents

“Information-rich” reproductive outcomes in carriers of a structural chromosome rearrangement ascertained on the basis of recurrent pregnancy loss Michelle.

A longitudinal study of the effects of free testosterone and other psychosocial variables on sexual function during the natural traverse of menopause

Antoni J. Duleba, M.D., Ibrahim M. Ahmed, M.D. Fertility and Sterility

Genetic Polymorphisms in the Polycomb Group Gene EZH2 and the Risk of Lung Cancer Kyong-Ah Yoon, MD, Hye Jin Gil, MS, Jihye Han, MS, Jaehee Park, MS,

A novel frameshift mutation in the 5α-reductase type 2 gene in Korean sisters with male pseudohermaphroditism Sung Hoon Kim, M.D., Kun Suk Kim, M.D.,

Geographic distribution of reproductive endocrinology and infertility (REI) fellowships in the United States Mary E. Abusief, M.D., Stacey A. Missmer,

Association study between single nucleotide polymorphisms in the VEGF gene and polycystic ovary syndrome Eung-Ji Lee, M.Sc., Bermseok Oh, Ph.D., Jong-Young.

Simvastatin improves biochemical parameters in women with polycystic ovary syndrome: results of a prospective, randomized trial Antoni J. Duleba, M.D.,

Cameron Gilbert, M. Sc. , Maria Valois, M. D. , FRCPC, Ph. D

Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.

Fertility and Sterility: an evaluation

Paolo Moghetti, M.D. Fertility and Sterility

Increased acylation-stimulating protein, C-reactive protein, and lipid levels in young women with polycystic ovary syndrome Yuwen Wu, M.D., Jianhua Zhang,

Yen-Ni Teng, Ph. D. , Yung-Ming Lin, M. D. , Hsiao-Fang Sunny Sun, Ph

Current evaluation of amenorrhea

A simplified novel laparoscopic formation of neovagina for cases of Mayer-Rokitansky- Küster-Hauser syndrome Atef Mohammad Darwish, M.D. Fertility and.

Tsan-Hon Liou, M. D. , Ph. D. , Jen-Hung Yang, M. D. , Ph. D

In vitro sildenafil citrate use as a sperm motility stimulant

Adiponectin levels reflect the different phenotypes of polycystic ovary syndrome: study in normal weight, normoinsulinemic patients Artemis Karkanaki,

Diabetes mellitus and insulin resistance in mothers, fathers, sisters, and brothers of women with polycystic ovary syndrome: a systematic review and meta-analysis

Is there a role for diet in ameliorating the reproductive sequelae associated with chronic low-grade inflammation in polycystic ovary syndrome and obesity?

A novel Arg615Ser mutation of androgen receptor DNA-binding domain in three 46,XY sisters with complete androgen insensitivity syndrome and bilateral.

Haplotype analysis of the matrix metalloproteinase-9 gene associated with advanced- stage endometriosis You Jung Han, M.D., M.S., Han-Na Kim, M.S., Jin-Kook.

Is chromosome testing of the second miscarriage cost saving

Presentation transcript:

A novel single nucleotide polymorphism of INSR gene for polycystic ovary syndrome Eung-Ji Lee, M.Sc., Bermseok Oh, Ph.D., Jong-Young Lee, Ph.D., Kuchan Kimm, M.D., Ph.D., Sook-Hwan Lee, M.D., Ph.D., Kwang- Hyun Baek, Ph.D. Fertility and Sterility Volume 89, Issue 5, Pages 1213-1220 (May 2008) DOI: 10.1016/j.fertnstert.2007.05.026 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Map of INSR on chromosome 19p13.3→19p13.2 (177 kb). The black blocks indicate coding the exons and the white blocks indicate 5′ and 3′ UTR. 9 sites of SNPs marked with asterisks (∗) were genotyped in a larger Korean population. Novel SNPs identified in this study are indicated using bold face. Numbers in parenthesis are the frequencies of minor alleles for each SNP. Fertility and Sterility 2008 89, 1213-1220DOI: (10.1016/j.fertnstert.2007.05.026) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions