A 50-year-old male with persistent abnormality on computed tomography (CT) despite anticoagulation for 1 year. a) CT scan showing an expansile low attenuation lesion in the right main pulmonary artery (arrow); b) 18F-fluorodeoxyglucose positron emission tom... A 50-year-old male with persistent abnormality on computed tomography (CT) despite anticoagulation for 1 year. a) CT scan showing an expansile low attenuation lesion in the right main pulmonary artery (arrow); b) 18F-fluorodeoxyglucose positron emission tomography with corresponding high uptake in keeping with pulmonary artery sarcoma. Note mediastinal soft tissue with increased uptake. Deepa Gopalan et al. Eur Respir Rev 2017;26:160108 ©2017 by European Respiratory Society