Fig. 3. Enhanced EGFR signaling in Rhbdf2P159L/P159L mice.

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Mitochondria localize to both the front and the rear of neutrophils.

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(A) Prdx1−/−MEFs and Prdx1+/+MEFs were stimulated with H2O2 as indicated. (A) Prdx1−/−MEFs and Prdx1+/+MEFs were stimulated with H2O2 as indicated. Protein.

Nat. Rev. Clin. Oncol. doi: /nrclinonc

Scanning electron microscopy analysis of EGK-I to -V chick embryos.

KIN-3 depletion leads to increased levels of centrosomal ZYG-1

Expression of mutant EGFR and downstream signaling components in tumors of mice at survival endpoint. Expression of mutant EGFR and downstream signaling.

Fig. 8. CCA and ChQ treatment induce accumulation of F-actin rings.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown AZ-521 cells. VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown.

Fig. 1. Chlamydia infection causes elevated levels of sortilin.

Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.

Fig. 7. Motion adaptation increases time-dependent response modulations (TDRM) relatively to the average cell response.TDRM normalized to the value obtained.

Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.

TC-1 silencing sensitized A549 and SPC-A-1 cells to radiation therapy

Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.

Fig. 1. Mitochondrial internalization in cardiomyocytes.

Fig. 5. Expression of either dFMRP or human FMRP does not induce eIF2α phosphorylation.(A) Analysis of eIF2α phosphorylation upon dFMRP expression. Expression.

Fig. 3. Inactivation of the Wnt/β-catenin signaling pathway inhibited cell proliferation and induced apoptosis in A549 and SPC-A-1 cells. Inactivation.

Fig. 4. The model of malate metabolism in fruit cells under different K level conditions. The model of malate metabolism in fruit cells under different.

Ectopic sprouting and proliferation in Rbpj veins.

Challenge with oxazolone results in epithelial hyperplasia and influx of inflammatory cells into the epidermis and dermis and keratosis as observed in.

Fig. 1. γ-Tubulin localizes in close proximity to centriole walls in interphase but within an extended PCM meshwork in mitosis.U2OS cells were fixed and.

Fig. 2. DDR1 over-expression enhances collagen fibril reorganization

Fig. 7. E2F1 acetylation in A1/A2-KO MEFs

Fig. 3. Mutation of Y520 and Y667 result in increased delivery of prestin to the apical surface of MDCK cells.MDCK cells transiently transfected with wt.

Fig. 8. Knockdown of Meis1 reduces the expression of Foxn4 and Lim1+2

Fig. 3. Characterization of unclassified cells (UCs).

Formation of papilloma lesions in the UroIICre+Fgfr3+/K644EK-RasG12D/+ model. Formation of papilloma lesions in theUroIICre+Fgfr3+/K644EK-RasG12D/+model.

Fig. 7. The sma gene is necessary for ampA mRNA accumulation and its loss phenocopies some ampA effects.(A) RT-PCR showing levels of ampA transcripts in.

Fig. 4. Non-autonomous rescue of puc expression in DME cells

Fig. 2. Ex vivo inducible knockout of PDCD2 in ESCs results in loss of S phase entry and increased p53.(A) Growth curve of inducible knockout and WT ESCs.

Fig. 5. The bulk of Cep135 localizes distantly from Sas-6 and STIL

Fig. 3. Cell-autonomous loss of GABAergic interneurons in the OB of newborn and adult conditional GFRα1 mutants. Cell-autonomous loss of GABAergic interneurons.

Fig. 6. Effect of SAHA and ML on histone acetylation, BAX, and p21CDKN1A expression.PANC-1 and BxPC-3 cells were incubated for 48 hours with 5 µM.

Fig. 5. Receptor tyrosine kinase activation in response to growth factor stimulation. Receptor tyrosine kinase activation in response to growth factor.

FAK tyrosine phosphorylation is unaffected by loss of LAR activity.

Fig. 2. Centrosomal proteins display distinct localizations and radial distances from centriole walls.U2OS cells were fixed and stained with the indicated.

Fig. 3. Rnd proteins induce stronger responses in subconfluent endothelial cells.HUVECs were transfected with Rnd1, Rnd2, Rnd3 or GFP-encoding plasmids.

Fig. 7. Representative images of control (Cas9+GFP) and Cas9+gRNA+GFP co-injected embryos on day 4 of culture, showing nuclear-imported GFP (green) and.

Fig. 1. TSA at 165 nM induces maximal acetylation of histone H3 and near-maximal acetylation of histone H4.Immunoblot analysis of acetylated histones H3.

Fig. 6. STK35 KO mice show ovary defects.

Fig. 6. Apical polarity of primitive endoderm cells on surface of embryoid bodies.Embryoid bodies were analyzed by immunofluorescence microscopy for GATA4.

An inhibitor of HSP90β reduces the level of HNF4A protein in hepatic progenitor cells. An inhibitor of HSP90β reduces the level of HNF4A protein in hepatic.

Fig. 1. Phenotypes of RasV12 transformed Drosophila lines

Fig. 1. Polarized F-actin cables in the Xenopus neural plate.

High-affinity mutants of β3 integrin fail to stimulate RhoA activity and fibronectin fibrillogenesis. High-affinity mutants of β3 integrin fail to stimulate.

Fig. 2. RFC3 function in chloroplasts.

Sox2 regulates dental epithelial stem cell proliferation and differentiation. Sox2 regulates dental epithelial stem cell proliferation and differentiation.

Fig. 1. The human tylosis mutation enhances secretion of AREG

Fgfr3;4 mutant lungs display an increase in Mfap5, Igf1 and Fbn2 expression. Fgfr3;4 mutant lungs display an increase in Mfap5,Igf1and Fbn2 expression.

Gα12 is not required for hepatic cystogenosis induced by Pkd1 knockout

AT1R–EGFR transactivation occurs in HMEC-LST-AT1R cells.

dcn1-deletion results in attenuated cohesin cleavage at anaphase

Expression of active Rho partially rescues Erk1/2 activation and peripheral FA phenotype in RIAM-knockdown cells. Expression of active Rho partially rescues.

Fig. 2. Expression of Cx43 mutant T154A resulted in non-radial spreading and formation of protrusions in J558µm3 cells spreading in response to BCR signaling.(A)

Fig. 2. Acetylation stiffens primary cilia.

Fig. 5. Testis defects in STK35 KO mice.

Histology of Brucella bone marrow foci in mice.

Fig. 3. MO-mediated smc3 knockdown results in reduced regenerate length, segment length and cell proliferation. MO-mediated smc3 knockdown results in reduced.

Histone crotonylation in kidney tubular cells.

Fig. 7. Analysis of dFMRP kinetics in dFMRP granules by FRAP

The absence of host Fbln5 results in increased apoptosis and decreased proliferation in Pan02 tumors. The absence of host Fbln5 results in increased apoptosis.

Lack of Ctip2 is associated with impaired proliferation and delayed onset of differentiation during early stages of epidermal development. Lack of Ctip2.

2DG suppresses of lamellipodia and filopodia and causes disorganization of F-actin filaments in murine endothelial cells. 2DG suppresses of lamellipodia.

Role of Src and PTP-PEST in upregulation of tyrosine phosphorylation of paxillin and FAK. (A) Mock and D11 cells were pre-incubated with PP2 or PP3 (10 µM,

Ca2+-mediated differentiation of primary mouse keratinocytes is independent of epiplakin. Ca2+-mediated differentiation of primary mouse keratinocytes.

Upon challenge with oxazolone, human leukocytes (mainly consisting of T cells) infiltrate the dermis and epidermis. Upon challenge with oxazolone, human.

Effect of overexpression of Gcs1p on mitochondrial morphology.

DGKζ and Cbl-b deficient T Cells have enhanced ERK1/2 and IκBα phosphorylation. DGKζ and Cbl-b deficient T Cells have enhanced ERK1/2 and IκBα phosphorylation.

Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8 and Stat3+/+:HPV8 mice. Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8.

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Fig. 3. Enhanced EGFR signaling in Rhbdf2P159L/P159L mice. Enhanced EGFR signaling in Rhbdf2P159L/P159L mice. (A) Immunohistochemical staining of Rhbdf2+/+ and Rhbdf2P159L/P159L skin sections with phospho-ERK1/2 and phospho-mTOR. Arrows indicate increased levels of phospho-ERK1/2 and phospho-mTOR staining. Scale bars: 100 μm. (B) Immunoblot analysis of cell lysates obtained from Rhbdf2+/+ and Rhbdf2P159L/P159L MEFs. Actin served as a loading control. Band intensities were quantified using ImageJ (https://imagej.nih.gov/ij/). (C) Immunohistochemical staining of Rhbdf2+/+ and Rhbdf2P159L/P159L skin sections with proliferation marker Ki-67. Quantification of proliferating cells was performed as described previously (Almeida et al., 2012). Scale bars: 100 μm. Vishnu Hosur et al. Biology Open 2017;6:1174-1179 © 2017. Published by The Company of Biologists Ltd