Tumor phenotyping. Tumor phenotyping. (A) Comparative growth behavior of tumors after grafting R versus VR J2A, H1, and I1 cell lines in independent experiments.

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Tumor phenotyping. Tumor phenotyping. (A) Comparative growth behavior of tumors after grafting R versus VR J2A, H1, and I1 cell lines in independent experiments analyzed at end point on day 21 (ANOVA statistics). (B) Comparative growth potential of VR versus R or VdR versus R tumors in independent experiments on J2A, H1, and I1 cell lines. Results are expressed as a ratio to normalize all experiments to 100%, corresponding to the growth of R tumors. (C, D) Comparative NMR metabolite analysis of R versus VdR (S2C: P = 0.33) and VR versus VdR tumors (S2C: P = 0.04) as described in the legend of Fig 2D. Caroline Giessner et al. LSA 2018;1:e201800073 © 2018 Naquet et al.