Twenty-Year Follow-Up of a Controlled Trial Comparing a Combination of Methotrexate Plus Cyclosporine with Cyclosporine Alone for Prophylaxis of Graft-versus-Host.

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Twenty-Year Follow-Up of a Controlled Trial Comparing a Combination of Methotrexate Plus Cyclosporine with Cyclosporine Alone for Prophylaxis of Graft-versus-Host Disease in Patients Administered HLA-Identical Marrow Grafts for Leukemia Mohamed L. Sorror, MD, Wendy Leisenring, ScD, H. Joachim Deeg, MD, Paul J. Martin, MD, Rainer Storb, MD Biology of Blood and Marrow Transplantation Volume 11, Issue 10, Pages 814-815 (October 2005) DOI: 10.1016/j.bbmt.2005.05.016 Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Kaplan-Meier product-limit estimates of overall survival among (A) CML patients and (B) AML patients, and (C) prevalence [2] of chronic GVHD in CML and AML patients, as stratified by the immunosuppressive regimen used: methotrexate/cyclosporine versus cyclosporine alone. CR indicates complete remission; CSP, cyclosporine; MTX, methotrexate. Biology of Blood and Marrow Transplantation 2005 11, 814-815DOI: (10.1016/j.bbmt.2005.05.016) Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions