The procedure of alloislet transplantation in T1D recipients.

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The procedure of alloislet transplantation in T1D recipients. The procedure of alloislet transplantation in T1D recipients. After procurement of a donated pancreas, islets are isolated from the organ through collagenase digestion and purified through centrifugation to separate the islet and acinar tissue. Thereafter, the islets are infused by gravity through a cannula that was introduced percutaneously through the liver and retrograde into the hepatic portal venous system. Portal venous blood flow distributes the islets throughout the liver. Reprinted with permission from Robertson (28). R. Paul Robertson Dia Care 2015;38:1030-1035 ©2015 by American Diabetes Association