Anaesthesia and epilepsy

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Anaesthesia and epilepsy A. Perks, S. Cheema, R. Mohanraj British Journal of Anaesthesia Volume 108, Issue 4, Pages 562-571 (April 2012) DOI: 10.1093/bja/aes027 Copyright © 2012 The Author(s) Terms and Conditions

Fig 1 Physiological changes occurring during prolonged status epilepticus. Adapted from Shorvon.106 PED, periodic epileptic discharge; CBF, cerebral blood flow. 1, Loss of reactivity of brain oxygen tension; 2, mismatch between the sustained increase in oxygen and glucose utilization and a decrease in cerebral blood flow; 3, a depletion of cerebral glucose and glycogen concentrations; 4, a decline in cerebral energy state. British Journal of Anaesthesia 2012 108, 562-571DOI: (10.1093/bja/aes027) Copyright © 2012 The Author(s) Terms and Conditions