A: Sagittal T1 view of the left hippocampus illustrating automated FreeSurfer hippocampal segmentation outlined in red. A: Sagittal T1 view of the left hippocampus illustrating automated FreeSurfer hippocampal segmentation outlined in red. Pixel-by-pixel analysis of the diffusion coefficient D of the gray matter (B), the perfusion fraction f (C), the pseudodiffusion D* (D), and the blood flow–related fD* (E) in a low cognitive–performing participant with type 2 diabetes. Frank C. van Bussel et al. Dia Care 2015;38:876-882 ©2015 by American Diabetes Association