Single 2-μm histological section from 140 serial sections used to quantify relative abundance of intravasating large protrusions, intravasating proplatelets,

Slides:



Advertisements
Similar presentations
Figure 1. - Right knee joint (articulatio genus)..
Advertisements

Decreased cell polarity and adhesion protein expression after 56Fe radiation. Decreased cell polarity and adhesion protein expression after 56Fe radiation.
Osteosarcoma histology.
Long-term decrease of IEC migration after 56Fe radiation relative to γ-rays. Long-term decrease of IEC migration after 56Fe radiation relative to γ-rays.
Impaired lymphatic valve protrusion in Tie2Cre;Piezo1cKO mice.
Poly-GR and poly-PR co-aggregate with ribosomal proteins in C9orf72 patients. Poly-GR and poly-PR co-aggregate with ribosomal proteins in C9orf72 patients.
Pigmentation in Rev3l-deleted interfollicular epidermis with wounding, UV radiation, or TPA application. Pigmentation in Rev3l-deleted interfollicular.
Both haematopoietic and non‐haematopoietic compartments are involved in myocarditis development.A.Kaplan‐Meier survival curves showing survival of bone.
Mitofilin cluster distribution is denser in the perinuclear mitochondria. Mitofilin cluster distribution is denser in the perinuclear mitochondria. (A)
Importin-β remains bound to NPCs after washing.
Quantitative assessment of articular cartilage morphology via EPIC-μCT
The IMS fuses to the plasma membrane at the protrusion tip.
Rapid vimentin reorganisation upon BCR stimulation.
CCL21 localizes to T cell zone FRCs in young and aged spleens.
Procedure for intravital CLEM.
Nonhematopoietic cells help regulate the pathogenic adaptive immune response during the second peak of joint swelling. Nonhematopoietic cells help regulate.
Proplatelets and large protrusions are morphologically distinct and possess different MT arrangements. Proplatelets and large protrusions are morphologically.
Impaired ECM protein synthesis in infarcted area of S100a4cre+/− × Fstl1flox/flox mice Impaired ECM protein synthesis in infarcted area of S100a4cre+/−
Elysse C. Filipe et al. BTS 2018;3:38-53
TrkB-T1 is upregulated in cerebellum of Pex14ΔC/ΔC BL/ICR mouse at P3.
The absence of the centrosome changes global microtubule dynamics in a migrating cell. The absence of the centrosome changes global microtubule dynamics.
Axonal swelling and impairment of dendritic development in Purkinje cells from Pex14ΔC/ΔC BL/ICR mouse upon treatment with BDNF. Axonal swelling and impairment.
Marker identification and quantification by StrataQuest, and confocal analysis of EV-containing tissue sections. Marker identification and quantification.
BDNF expression in the cerebellum and brain stem region.
Inhibition of VEGFA or macrophage-specific ablation of Vegfa from TIE2hi/VEGFAhi TMEM macrophages reduces vascular permeability and tumor cell intravasation.
BMDC-EV attract immune cells in lymph nodes similarly as in the skin.
Renal Fibrosis and Plasma Creatinine Levels at 18 Weeks Post TAC (A) Plasma creatinine levels. (B) Representative images (original magnification ×20) of.
Defect of cerebellar development and malformation of Purkinje cells in Pex14ΔC/ΔC BL/ICR mice. Defect of cerebellar development and malformation of Purkinje.
Commissural Wt1+ neurons.
VEGFC treatment improves kidney histology and survival in Cys1cpk/cpk mice. VEGFC treatment improves kidney histology and survival in Cys1cpk/cpk mice.
Nuclear DNA signal is altered in Chd5-deficient NSCs.
Mitotic chromosome misalignment is independent of DNA replication.
FAM134B-2 colocalizes with SERCA2 and SEC62.
Treatment with MI-773 causes changes in p53 status.
Elysse C. Filipe et al. BTS 2018;3:38-53
Distribution of splenic T cells, B cells, and NK cells in NSG hL-7xhIL-15 humanized mice. Distribution of splenic T cells, B cells, and NK cells in NSG.
Changes in mutation rate or protein abundance are not observed in HATs when comparing rho+ to rho0 cells. Changes in mutation rate or protein abundance.
Pericytes promote epidermal regeneration in OCs that most closely resembles human skin epidermis. Pericytes promote epidermal regeneration in OCs that.
Lack of Vnn1 is associated with the development of aggressive skin STS
Megakaryocytes can produce multiple large protrusions simultaneously that anchor into the endothelium. Megakaryocytes can produce multiple large protrusions.
Megakaryocyte total surface area increases with protrusion extension.
Live-cell imaging of transcriptional activation following TSA treatment. Live-cell imaging of transcriptional activation following TSA treatment. (A) Frames.
TSA causes premature chromatid sister separation.
No correlation between the position of the gene in the nuclear volume and the transcription levels on each of the alleles. No correlation between the position.
Fig. 1. Morphological and growth characterization of hBMCs and hPDCs
High-affinity binding to the hypervariable region of the β1 I-like domain controls signaling to fibronectin fibrillogenesis. High-affinity binding to the.
DDR1 plays an intrinsic role in primary epithelial cells undergoing branching morphogenesis and is required for correct organization of the basement membrane.
Fig. 2. Fluorescent images indicating the cytoskeleton of human bone marrow-derived mesenchymal stem cells (hBMSCs) subjected to cyclic stretching. Fluorescent.
The mutants exhibit congenital hypothyroidism.
Rgs16::GFP expression in pancreatic neoplasia.
Diagrammatic representation of thrombopoiesis in vivo.
Representative histological sections of porcine lungs obtained after transbronchial cryoablation. Representative histological sections of porcine lungs.
The autophagy pathway is not required for STx2B trafficking.
Deletion of Sox2 in adult mice inhibits incisor regeneration.
DHA restores peroxisome morphogenesis in AOx- and D-BP-defective fibroblasts. DHA restores peroxisome morphogenesis in AOx- and D-BP-defective fibroblasts.
Prophase nuclear movements in wild-type, rec8 and rec7 mutant cells.
IGF1R is present in endometrial luminal epithelium at the receptive phase. IGF1R is present in endometrial luminal epithelium at the receptive phase. Endometrial.
Residual enzymatic activity in media or cell lysates containing 1G244 and titration of 1G244-induced cell death in B6Nlrp1b+ BMDMs. Residual enzymatic.
Megakaryocytes predominantly enter the circulation as a large protrusion. Megakaryocytes predominantly enter the circulation as a large protrusion. (A)
Megakaryocyte large protrusions can be observed by intravital correlative EM. Megakaryocyte large protrusions can be observed by intravital correlative.
Histology of Brucella bone marrow foci in mice.
Networks of CR and NCR cells in reeler layer 1
Fear discrimination is restricted to the Te1–PL cortex pathway.
Association of NM-HA and NM-GFP with SGs is transient.
DBZ treatment can induce virtually complete exfoliation of BE epithelium. DBZ treatment can induce virtually complete exfoliation of BE epithelium. (A,B)
Antigen-specific CD8+ T cells express higher levels of PD-1 in animals that received the optimized SSX2 vaccine. Antigen-specific CD8+ T cells express.
Representative macrophage staining images only from the knee joints of CAIA mice injected s.c. with GalNAc–MASP-3–siRNA duplex 2 or GalNAc–luciferase–siRNA.
Example inverse FF-OCT images (left column) and corresponding histology images (right column) of ovarian metastases. Example inverse FF-OCT images (left.
Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8 and Stat3+/+:HPV8 mice. Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8.
Whole mounts (A-D; ×20), and H&E sections (E-H, ×100) of the mammary gland. Whole mounts (A-D; ×20), and H&E sections (E-H, ×100) of the mammary gland.
Presentation transcript:

Single 2-μm histological section from 140 serial sections used to quantify relative abundance of intravasating large protrusions, intravasating proplatelets, free large protrusions, and free proplatelets. Single 2-μm histological section from 140 serial sections used to quantify relative abundance of intravasating large protrusions, intravasating proplatelets, free large protrusions, and free proplatelets. Bone marrow of the diaphysis region obtained from flushed femurs. Scale bar represents 100 μm. Image representative of three independent experiments. Edward Brown et al. LSA 2018;1:e201800061 © 2018 Brown et al.