Effect of M-cadherin RNAi on serum-starvation-induced apoptosis.

Slides:

Advertisements

Similar presentations

Fig. 3. Effect of JGH43IA on the glutamate-induced DNA fragmentation

Advertisements

Supplemental Digital Content 4

Nm23-H1 Regulates Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells via Arf6-Rac1 Signaling Axis Cell Physiol Biochem 2013;32: DOI: /

The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib Yiyu Zou, PhD, Yi-He.

Protective Role of Mitochondrial Peroxiredoxin III against UVB-Induced Apoptosis of Epidermal Keratinocytes Jin Young Baek, Sujin Park, Jiyoung Park,

PMAIP1/NOXA gene amplification increases DLBCL vulnerability to BCL2 inhibitors. PMAIP1/NOXA gene amplification increases DLBCL vulnerability to BCL2 inhibitors.

Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia by Xue-Fei Huang, Shao-Kai Luo,

GM-CSF induces tumor cell EMT and stemness.

Marissa V. Powers, Paul A. Clarke, Paul Workman Cancer Cell

Volume 74, Issue 10, Pages (November 2008)

Proline supplementation during P5CS protein knockdown suppressed GCN2 activation. Proline supplementation during P5CS protein knockdown suppressed GCN2.

Marissa V. Powers, Paul A. Clarke, Paul Workman Cancer Cell

The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib Yiyu Zou, PhD, Yi-He.

Supplementary Figure 2. Effect of IL-32 and siRNA of IL-32 on melanoma, colon and prostate cancer cell growth and apoptosis as well as IL-32 expression.

Fig. 3. Wisper controls CF behavior and survival.

FIP200 deficiency alters mitochondria activation and ROS production in T cells. FIP200 deficiency alters mitochondria activation and ROS production in.

HA-specific Abs in serum 14 d after a single vaccination with the various targeted DNA vaccines. HA-specific Abs in serum 14 d after a single vaccination.

Expression of SYCE2 activates the DSB repair pathway.

DIO2 modifies inflammatory responses in chondrocytes

A20 inhibits caspase-8 cleavage and TRAIL-induced apoptosis.

Volume 133, Issue 5, Pages (November 2007)

Downregulation of SPRY4 expression is associated with FGFR1–FRS2 activation. Downregulation of SPRY4 expression is associated with FGFR1–FRS2 activation.

LFA-1 is present in cytosolic clusters similar to those containing RhoB and tubulin in migrating T lymphocytes, and reducing RhoB abundance impairs the.

Valproic acid (VPA) synergises with VAC (mafosfamide, doxorubicin and vindesine) to induce apoptosis in small cell lung carcinoma (SCLC) cell lines. Valproic.

ROS induction and ATR inhibition synergize in inducing multiple myeloma (MM) cell death. ROS induction and ATR inhibition synergize in inducing multiple.

TRAF4 is required for EGFR activation in response to EGF stimulation.

RNAi screen for host factors involved in L. monocytogenes dissemination. RNAi screen for host factors involved in L. monocytogenes dissemination. (A) Images.

Specific inhibition of Ras, but not Rac, inhibits EGF-stimulated protrusion. Specific inhibition of Ras, but not Rac, inhibits EGF-stimulated protrusion.

Blockage of peroxisomal FAO induces differentiation on activated satellite cells. Blockage of peroxisomal FAO induces differentiation on activated satellite.

NFAT5+/- muscle cells are less motile.

Fig. 1. Loss of PC following INT depletion

Effect of GSK-3β inhibition on serum-starvation-induced apoptosis.

Effect of M-cadherin RNAi and GSK-3β inhibition on myogenic differentiation of C2C12 myoblasts. Effect of M-cadherin RNAi and GSK-3β inhibition on myogenic.

SLK/LOK-phosphorylated and activated ezrin prevents MISP localization at the cell cortex. SLK/LOK-phosphorylated and activated ezrin prevents MISP localization.

Loss of ezrin and MISP leads to the formation of cysts containing multiple lumens and spindle orientation defects. Loss of ezrin and MISP leads to the.

Effect of the siRNA-mediated knockdown of endogenous MARCH8 on the expression levels of MARCH8 substrates, TfR and CD98, in HepG2 cells. Effect of the.

SW fraction induces S phase arrest and apoptosis.

S. cerevisiae Bre1p confers resistance to apoptosis induced by H2O2.

Downregulation of caveolin-1 by si-RNA in NIH3T3 cells increased survivin expression. Downregulation of caveolin-1 by si-RNA in NIH3T3 cells increased.

Fig. 6. RhoB is required for Rnd3-induced stress fibre formation

FAK is required for LPA-mediated induction of trailing-edge retraction and the restoration of normal morphology. FAK is required for LPA-mediated induction.

Proliferative and morphological defects following TbCALM and TbEpsinR depletion. Proliferative and morphological defects following TbCALM and TbEpsinR.

Engagement of PDGF-αR and PDGF-βR is critical for PDGF-BB-mediated increased proliferation of NPCs. RT-PCR (A) and WB (B) of PDGF-αR and PDGF-βR in NPCs;

Effect of M-cadherin RNAi on apoptosis in confluent C2C12 myoblasts.

Telomere cohesion is established in S phase in cohesin-ring-depleted cells. Telomere cohesion is established in S phase in cohesin-ring-depleted cells.

Increased pancreatic insulin content and islet size and protection against HFD- and palmitate-induced cell death in PKCδKN-overexpressing mice. Increased.

Apoptosis in CAM vessels after staining with TUNEL

Interaction between the G6PC2 rs G and rs G alleles on G6PC2 promoter activity. βTC-3 cells were transiently cotransfected, as described.

Effect of GSK-3β inhibition on cell-confluence-induced apoptosis.

Targeting eIF4E increases ZEB1 protein and mRNA levels and decreases ZEB1-targeting miR-200c and miR-141 microRNAs. Targeting eIF4E increases ZEB1 protein.

Effects of PS-341 on apoptosis in orthotopic human pancreatic tumors.

The human colonic monocarboxylate transporter Isoform 1: Its potential importance to colonic tissue homeostasis Mark Cuff, Jane Dyer, Mark Jones, Soraya.

CCG regulates cellular localization and blocks target gene expression of MRTF. A, SK-Mel-147 cells were cotransfected with RhoC and the SRE.L reporter.

Mcl-1 knockdown promotes cleavage of caspase-3 in nonadherent melanoma cells. Mcl-1 knockdown promotes cleavage of caspase-3 in nonadherent melanoma cells.

A, iDC (top) or mDC (bottom) were loaded with or without 10 pfu/cell reovirus, and cultured with Mel-888 cells in the presence of blocking serum. A, iDC.

Effect of IL24 on phosphorylation of eIF2α and proliferation in cancer cells. Effect of IL24 on phosphorylation of eIF2α and proliferation in cancer cells.

T-cell activation and induction of apoptosis in epithelial cells of oral lesions induced by 4-NQO. T-cell activation and induction of apoptosis in epithelial.

Secretion of TNF-α from macrophages and monocytic cells were reduced by the deletion of Nrdc. Secretion of TNF-α from macrophages and monocytic cells were.

Fig. 2 Viperin promotes methionine oxidation of KSHV helicase.

Per1 inhibits growth and induces apoptosis in prostate cancer cell lines. Per1 inhibits growth and induces apoptosis in prostate cancer cell lines. LNCaP,

Expression of the cell death markers activated caspase-3 and LC3 I/II in TUBO cells. Expression of the cell death markers activated caspase-3 and LC3 I/II.

Adhesion to fibronectin protects Mcl-1 knockdown cells from apoptosis.

Knockdown of ERBB3, NRG1, or ERBB2 in H358-TwistER cells reduces basal PI3K–AKT signaling and ablates serum-independent proliferation before EMT. A and.

CCR5 enhances both HDR and SSA DNA repair.

Omomyc-induced cytoskeletal reorganization and increased apoptosis in C2C12 cells. Omomyc-induced cytoskeletal reorganization and increased apoptosis in.

Target-dependent T cell–mediated cytotoxicity of HER2-TDB.

Sorafenib inhibits cell proliferation and induces apoptosis in HCC cells. Sorafenib inhibits cell proliferation and induces apoptosis in HCC cells. A,

EGF induces HPSE nucleolar localization in human BMBC cells.

A, indicated model systems were cultured in media containing complete serum, harvested, and lysed; total protein was separated by SDS-PAGE, transferred.

WEE1 inhibition followed by TRAIL treatment results in apoptotic cell death in MB231 cells. WEE1 inhibition followed by TRAIL treatment results in apoptotic.

Presentation transcript:

Effect of M-cadherin RNAi on serum-starvation-induced apoptosis. Effect of M-cadherin RNAi on serum-starvation-induced apoptosis. M-cadherin RNAi (M-), non-targeted scrambled siRNA-transfected (SiCON) or normal control (NC) C2C12 myoblasts were serum starved from zero to 48 hours before being harvested. *P<0.05 vs both SiCON and NC control groups. The data are shown as the mean ± s.e.m. of three independent experiments. (A) Mitochondria were isolated from attached cells after serum starvation for 0 hours (SS-0h), 6 hours (SS-6h), 12 hours (SS-12h), 24 hours (SS-24h) or 48 hours (SS-48h). The mitochondria Δψm (orange to green ratio) was evaluated by FACS analysis of JC-1 staining. (B) DNA fragmentation in attached cells was measured by a cell death ELISA at the same time points as described in A. (C) The percentage of cells undergoing apoptosis in both attached and floating cells was defined as: (total TUNEL-positive attached cells + total TUNEL-positive floating cells)/(total attached cells + total floating cells). Yan Wang et al. J Cell Sci 2011;124:3835-3847 © 2011.