Healthy volunteers (n=28) P value CRC patients 　　　　　　　 (n=30) 0.155 62.3±9.3

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Supplemental Table 1.　Characteristics of serum chemokine study subjects Healthy volunteers (n=28) P value CRC patients 　　　　　　　 (n=30) 0.155 62.3±9.3 66.2±11.0 Age (years) N.A. 25/5 Tumor location (Colon/Rectum) 0.178 5500±900 6100±2000 White blood cell counts (/ul） 0.088 1800±610 1490±600 Lymphocytes cell counts (/ul） 20/10 Nodal metastasis (+/-) 13/17 Distant metastasis (+/-) 4/6/7/13 TNM Stage (Ⅰ/Ⅱ/Ⅲ/Ⅳ) 23/4/3 Treatment (Surgery/Chemo therapy/None) Data are expressed as means±SD. * CRC: Colorectal cancer 0.107 9/19 17/13 Gender (male/female) 0.220 320±100 380±170 Monocytes cell counts (/ul） 0.196 3400±860 3900±1690 Neutrophils cell counts (/ul） Table 1